Results 91 to 100 of about 3,653,860 (344)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Construction and demolition waste management in China through the 3R principle
, 2018 Construction and demolition waste (CDW) accounts for 30% to 40% of the total amount of waste in China. CDW is usually randomly dumped or disposed in landfills and the average recycling rate of CDW in China is only about 5%.
Bei-Jia Huang +5 more
semanticscholar +1 more source
Hierarchical dynamics as a macroscopic organizing principle of the human brain
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Accumulating evidence suggests that, during task performance, information is encoded at shorter timescales in primary sensory regions as compared to longer timescales in higher-order cortical regions. These encoding timescales correlate with
Ryan V. Raut, A. Snyder, M. Raichle
semanticscholar +1 more source
Journal of Magnetic Resonance, 2011 The circumstances surrounding the realisation that NMR signal reception could be quantified in a simple fundamental manner using Lorentz's Principle of Reciprocity are described. The poor signal-to-noise ratio of the first European superconducting magnet is identified as a major motivating factor, together with the author's need to understand phenomena
openaire +3 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
THE DESIGN OF A CATAPULT MACHINE
Journal of Industrial Design and Engineering Graphics, 2021 This article will present the elements of the external structure of the catapulting machine, together with the catapulting mechanism and the operating principle of the whole assembly.
Matei Toma
doaj
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2019 The paper analyzes the theoretical approaches to the definition and analysis of the content of education and the content of teaching in didactics. It is concluded that the process of changing the concept of the content of education and training is ...
Elena V. Buntova
doaj +1 more source
Milletleraras, 1980 Mustafa Kemal Atatürk (1881- 1938) is not generallyknown as a "builder" of theories. it was his deliberatechoice not to leave behind an "inflexible doctrine". Hewanted his teachings to be dynamic views suiting the needto become contemporary in every way. Ideologies, no doubt.play a role in all regimes.
openaire +2 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Does Quantum Mechanics Clash with the Equivalence Principle – and Does it Matter? [PDF]
, 2010 With an eye on developing a quantum theory of gravity, many physicists have recently searched for quantum challenges to the equivalence principle of general relativity.
Elias Okon +3 more
core +1 more source