Results 101 to 110 of about 2,159,427 (297)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Imperfect Commitment and the Revelation Principle [PDF]

open access: yes
This paper extends the revelation principle to environments in which the mechanism designer cannot fully commit to the outcome induced by the mechanism.
Helmut Bester, Roland Strausz
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The principle of fairness : theory, defence, and application [PDF]

open access: yes
Theories of social justice propose various principles for the just regulation of social institutions and practices. However, why should individuals comply with the rules of just social institutions?
Kim, Dong-il
core  

Einstein, the reality of space, and the action-reaction principle [PDF]

open access: yes, 2013
Einstein regarded as one of the triumphs of his 1915 theory of gravity - the general theory of relativity - that it vindicated the action-reaction principle, while Newtonian mechanics as well as his 1905 special theory of relativity supposedly violated ...
Brown, Harvey   +4 more
core  

BANKING ETHICS: MAIN CONCEPTIONS AND PROBLEMS [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2014
Banking ethics is a specialized set of ethical standards and rules that should be followed in the activities of financial institutions and employees of the banking sector.
VALENTINA FETINIUC, IVAN LUCHIAN
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Corporations Law : In Principle

open access: yes, 2009
8th ed.Tony Ciro and Christopher Symes1. History, administration and reform -- 2. Types of companies -- 3. Registration -- 4. Consequences of registration -- 5. Internal rules -- 6. Management of companies -- 7.
Symes, C., Ciro, T.
core  

THE REALIZATION OF DIDACTIC PRINCIPLES IN THE FORMING OF SPEECH CULTURE PROFESSIONALS IN SERVICE AND TOURISM

open access: yesВестник Северо-Кавказского федерального университета, 2022
In article it is considered and proved the necessity of culture and speech culture training of personel on service and tourism. Are also analysed the all-didactic principles of training, that used to form of linguistic in- tensive personality of students
Helen Pavlovna Popova
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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