Results 61 to 70 of about 45,105 (328)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Formal Semantics: Origins, Issues, Early Impact

open access: yesThe Baltic International Yearbook of Cognition, Logic and Communication, 2010
Formal semantics and pragmatics as they have developed since the late 1960's have been shaped by fruitful interdisciplinary collaboration among linguists, philosophers, and logicians, among others, and in turn have had noticeable effects on developments ...
Barbara H. Partee
doaj   +1 more source

Unsupervised Dialogue Act Induction using Gaussian Mixtures

open access: yes, 2017
This paper introduces a new unsupervised approach for dialogue act induction. Given the sequence of dialogue utterances, the task is to assign them the labels representing their function in the dialogue.
Brychcín, Tomáš, Král, Pavel
core   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Can we Derive the Principle of Compositionality (if we Deflate Understanding)?

open access: yesDialectica, 2009
Paul Horwich has claimed that we can derive a certain form of the principle of compositionality from a deflationary account of what it is to understand a complex expression. If this were the case, we would realize a surprising theoretical economy, and if the derivation involved basic ideas from a use theory of meaning, we would have a novel argument ...
openaire   +1 more source

How to Hintikkize a Frege [PDF]

open access: yes, 2016
The paper deals with the main contribution of the Finnish logician Jaakko Hintikka: epistemic logic, in particular the 'static' version of the system based on the formal analysis of the concepts of knowledge and belief.
Schang, Fabien
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Morphologically Complex Predicates in Japanese and What They Tell Us About Grammar Architecture [PDF]

open access: yes, 2001
In this paper we take a fresh look at an old problem, the syntax and semantics of Japanese causatives. We demonstrate some seldom-noted similarities causatives bear to other Japanese morphologically complex predicates and argue why these similarities are
Cipollone, Domenic
core   +1 more source

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