Results 61 to 70 of about 1,382,324 (319)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Answering a Basic Objection to Bang/Crunch Holography

, 2004
The current cosmic acceleration does not imply that our Universe is basically de Sitter-like: in the first part of this work we argue that, by introducing matter into *anti-de Sitter* spacetime in a natural way, one may be able to account for the ...
A. Kehagias, A. Melchiorri, B. Feng, B. McInnes, B. McInnes, B.A. Bassett, B.F. Roukema, B.S. Acharya, B.S. Acharya, Brett McInnes, C.V. Johnson, D. Klemm, D.H. Coule, E. Babichev, E. Witten, E. Witten, E. Witten, E.V. Linder, F. Leblond, G. Jungman, H.B. Lawson, I. Gott, I.P. Neupane, J. Maldacena, J.A. Wolf, J.J. Blanco-Pillado ., J.K. Erickson, J.M. Maldacena, J.P. Gauntlett, K. Choi, K. Nomizu, L. Jarv, L. Maoz, M. Alishahiha, M. Cvetic, N. Goheer, N. Turok, O. Lahav, P.F. Gonzalez-Diaz, P.J. Steinhardt, P.K. Townsend, P.S. Corasaniti, R. Britto-Pacumio, R. Cardenas, R. Kallosh, R.P. Geroch, S. Cacciatori, S. Gukov, S. Hellerman, S. Lee, S. Wang, S. Watson, S.M. Carroll, S.W. Hawking, T. Banks, T. Battefeld, T. Hertog, U. Alam, U. Alam, U. Alam, U. Seljak ., V. Balasubramanian, V. Balasubramanian, V. Balasubramanian, W. Fischler, W. Fischler   +65 more
core   +1 more source

The Metaphysics of Free Will: A Critique of Free Won’t as Double Prevention [PDF]

, 2015
The problem of free will is deeply linked with the causal relevance of mental events. The causal exclusion argument claims that, in order to be causally relevant, mental events must be identical to physical events.
Grasso, Matteo
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

EL PRINCIPIO DEL DOBLE EFECTO Y SU RELEVANCIA EN EL RAZONAMIENTO JURÍDICO THE DOUBLE EFFECT PRINCIPLE AND ITS RELEVANCE TO JURIDICAL INTERPRETATION

Revista Chilena de Derecho, 2008
En este trabajo el autor intenta mostrar la relevancia que le corresponde al principio del doble efecto en el razonamiento práctico general y especialmente en el razonamiento jurídico. Para ello procede del siguiente modo.
Alejandro Miranda Montecinos
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Balancing Acts: Intending Good and Foreseeing Harm -- The Principle of Double Effect in the Law of Negligence [PDF]

, 2005
In this article, responding to assertions that the principle of double effect has no place in legal analysis, I explore the overlap between double effect and negligence analysis.
Lyons, Edward C.
core  

Effects of New Gravitational Interactions on Neutrinoless Double Beta Decay [PDF]

, 2000
It has recently been proposed that violations of Lorentz invariance or violations of the equivalence principle can be constrained from the non-observation of neutrinoless double beta decay.
Klapdor--Kleingrothaus, H. V., Päs, H., Sarkar, U.   +2 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Pionic Contribution to Neutrinoless Double Beta Decay

, 2009
It is well known that neutrinoless double decay is going to play a crucial role in settling the neutrino properties, which cannot be extracted from the neutrino oscillation data.
Faessler, Amand, Toki, H., Vergados, J. D.   +2 more
core   +1 more source