Results 61 to 70 of about 166,432,767 (294)
CES Transactions on Electrical Machines and Systems, 2018 This paper presents a cost-effective driving system for automotive applications based on a double rotor electrically excited flux switching machine (FSM).
Xing Zhao
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Analysis of Symmetry and Motion Performance of the Transmission Mechanism of Reciprocating Cutter
Jixie chuandong, 2015 In order to keeping the furthest symmetry of the blade upper and lower moving while the reciprocating cutter of double blade running continuously,the transmission mechanism motion mode of the double blade reciprocating cutter is researched analyzed ...
Wang Hao, Yin Zhihong
doaj
MATEC Web of Conferences, 2016 This paper presents a double frequency conductivity measurement method for measuring mine bursting water, to solve the capacitance effect of the conductivity sensor itself has the help.
Zhou Mengran +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Applying the Principle of Double Effect [PDF]
, 2013 When ethical conflicts arise in clinical cases, physicians may need specific guidelines to help justify the decisions they make for the best interest of their patients.
Quirindongo, Andria E.
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
In Incognito: The Principle of Double Effect in American Constitutional Law [PDF]
, 2005 : In Vacco v. Quill, 521 U.S. 793 (1997), the Supreme Court for the first time in American case law explicitly applied the principle of double effect to reject an equal protection claim to physician-assisted suicide.
Lyons, Edward C.
core +3 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source