Results 41 to 50 of about 159,772 (309)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Конституционность как основополагающий принцип нормотворчества [PDF]

, 2013
CONSTITUTIONALITY AS THE BASIC PRINCIPLE OF RULE-MAKING P. SOLOVYEV The principle of constitutionality in law-making is studied. The content of the principle of constitutio-nality in terms of jurisprudence and legislation is disclosed. The ratio of the
Соловьев, П. В.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Editorial of Dossier “Criminal res iudicata, principle of legality, principle of culpability”

Revista Brasileira de Direito Processual Penal, 2018
What’s the meaning of the locution “medesimo fatto” in the Art. 649 of the Italian Criminal Procedure Code, that regulates the ne bis in idem principle (double jeopardy clause)? The fact object of the second judgment must be considered on its exclusively
Francesco Caprioli
doaj   +1 more source

Two conceptions of legal principles [PDF]

Anali Pravnog fakulteta u Beogradu, 2017
The paper discusses the classical understanding of legal principles as the most general norms of a legal order, confronting it with Dworkin's and Alexy's understanding of legal principles as prima facie, unconditional commands. The analysis shows that the common, classical conception brings into question the status of legal principles as norms, by ...
openaire   +2 more sources

Pertentangan Asas Legalitas Formil Dan Materiil Dalam Rancangan Undang-undang Kuhp [PDF]

, 2015
This study discusses on the contradiction of formal and material legality principle in the KUHP bill. The questions posed in this research is what are the forms of said contradiction between the formal and material legality principle in the KUHP bill ...
Tabiu, R. (Ramadan)
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The Principle of Legality in Islamic Criminal Justice System [PDF]

Hazara Islamicus, 2018
This work focuses on the principle of legality and the various other maxims regarding the rights of the accused under Islamic criminal justice system. Its main findings are: that the principle of legality (mabda’ al-Ibahat) is the most basic principle ...
Muhammad Munir
doaj  

Global Law as Intercontextuality and as Interlegality [PDF]

, 2019
Since the 1990s the effects of globalization on law and legal developments has been a central topic of scholarly debate. To date, the debate is however marked by three substantial deficiencies which this chapter seeks to remedy through a ...
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core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source