Results 211 to 220 of about 9,430 (279)

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

Psychometric validation of the Chinese version of the PROMIS-29 profile in community-dwelling older adults with multimorbidities. [PDF]

Front Public Health
Zhao T, Zhang Y, Cui Q, Zhang M, Han X, Chen J, Xu H.   +6 more
europepmc   +1 more source

Can Indonesia achieve universal health coverage? Organisational and financing challenges in implementing the national health insurance system.

SSM Health Syst
Susilo D, Wulandari LPL, Sukmayeti E, Asante A, Jan S, Thabrany H, Tangcharoensathien V, Wiseman V, Liverani M.   +8 more
europepmc   +1 more source

Determinants of Government Expenditures with Health Insurance Beneficiaries in the Brazilian Health System. [PDF]

Healthcare (Basel)
Moreira L, de Lima JVMT, Silvestrini MM, Sarti FM.   +3 more
europepmc   +1 more source

European sovereign debt control through reinforcement learning. [PDF]

Front Artif Intell
Khundadze T, Semmler W.
europepmc   +1 more source

Rethinking Tax-Transfer Policy for 21st Century Canada [PDF]

Andrew Sharpe, Fred Gorbet, Robin Boadway   +2 more
core  

Defining and reporting exercise intensity in interventions for older adults: a modified Delphi process. [PDF]

Eur Rev Aging Phys Act
Wollesen B, Herden M, Lamberti N, Giannaki CD.   +3 more
europepmc   +1 more source