Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
3D-printed Recoverable Microdrive and Base Plate System for Rodent Electrophysiology
Mihály Vöröslakos +6 more
openalex +2 more sources
The application of 3D-printed oral stents in intensity-modulated radiotherapy for oropharyngeal cancer and their dosimetric effect on organs at risk [PDF]
Jungang Ma +11 more
openalex +1 more source
International print and digital repositories initiatives in the United States: CRL, Portico, LOCKSS, Internet Archive : print archives in the United States [PDF]
A number of pressures on academic libraries imperil the long-term survivability of printed knowledge and heritage materials. Ever-growing volumes of materials, costs of preserving and delivering paper-based research resources, and researchers’ growing ...
Simon, James
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Improved Mixed-Integer Linear Programming Model for Short-Term Scheduling of the Pressing Process in Multi-Layer Printed Circuit Board Manufacturing [PDF]
Teeradech Laisupannawong +2 more
openalex +1 more source
Comparison of support structure generation techniques for 3d printing [PDF]
Master's Project (M.S.) University of Alaska Fairbanks, 2016As the old patents from the late 1980's and early 1990's expire, additive fabrication and rapid prototyping has seen a boom in recent years. Often called 3D printing, in the additive fabrication
Tupek, Ann
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Selling pictures: the illustrated auction catalogue [PDF]
This essay is based upon a survey of reproductions in auction catalogues – from their first appearance in the early eighteenth century until their more consistent use in the second decade of the twentieth century.
Elizabeth Pergam
doaj

