Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Measurement of age-of-acquisition in morphologically rich languages: Insights from Kannada and Filipino. [PDF]
Dulay KM +4 more
europepmc +1 more source
3-D printed high-gain elliptic flat Luneburg lens
Xin Che, Ju Gao, Zonghui Li
openalex +1 more source
The NIH 3D Print Exchange: A Public Resource for Bioscientific and Biomedical 3D Prints
Meghan Coakley +11 more
semanticscholar +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Dermatoglyphics as a Risk Indicator for Anterior Cruciate Ligament Injuries in Futsal Athletes. [PDF]
Soares BH +4 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The effect of nitrogen atmosphere during post-curing on cytotoxicity, polishability, flexural strength, and surface hardness of 3D-printed denture bases: an in vitro study. [PDF]
Gladrow K +6 more
europepmc +1 more source
One size does not fit all: The case for tailoring print materials
M. Kreuter, V. Strecher, B. Glassman
semanticscholar +1 more source

