Results 111 to 120 of about 20,103,050 (254)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Parution : Introduction to Contemporary Print Culture: Book as Media

open access: yes, 2020
Simone Murray, Introduction to Contemporary Print Culture: Books as Media, Routledge, 2020.    Introduction to Contemporary Print Culture examines the role of the book in the modern world.
Anaïs Goudmand
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

A Note on Pricing and Efficiency in Print Media Industries [PDF]

open access: yes
Actors on print media markets face two different (and interrelated) demand curves: the demand for copies and the demand for advertising space. This paper develops a realistic, yet simple, model of print media industries.
Kaiser, Ulrich
core  

Print- May 27, 1970 [PDF]

open access: yes, 1970
https://neiudc.neiu.edu/print/1134/thumbnail ...
Staff, Print
core  

THE DISTRIBUTION NETWORK DEVELOPEMENT IN PRINT MEDIA [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2012
In this article, we identify the characteristics of the distribution networks in print media and the features ofmarketing in mass media, emphasising the attempts initiated by the press in the context of the financial crisis.
Loredana Iordache   +2 more
doaj  

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