Results 101 to 110 of about 57,041 (306)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

A quantitative exploration of flight prioritisation principles, using new delay costs

, 2012
New costs of delay to the airline are presented for a range of aircraft and by phase of flight. It is shown how these costs may be suitable for cost optimisations during flight prioritisation decision-making.
Cook, A.J., Tanner, G.
core   +1 more source

Time-based prioritisation of performance measurement

, 1997
This paper looks at time-based prioritisation of performance ...
Carrie, Allan, Suwignjo, P., Bititci, Umit   +2 more
core   +2 more sources

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Scoping review protocol on research prioritisation for preparedness and response to outbreaks of high consequence pathogens

Open Research Europe
Background Prioritisation of research activities for infectious disease pathogens is usually undertaken through the identification of important research and knowledge gaps.
Emilia Antonio, Dorothy Chepkirui, Shanthi Levanita, Susan Khader Ibrahim, Isabel Foster, Eli Harriss, Louise Sigfrid, Alice Norton   +7 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Exploring current approaches towards patient prioritisation for clinical pharmacy services in UK mental health inpatient care

BMC Psychiatry
Background Mental health services in the United Kingdom (UK) are experiencing heightened pressures due to an increase in the number of patients accessing secondary mental health services amidst a period of workforce and funding constraints.
Fatima Q. Alshaikhmubarak, Richard N. Keers, Petra Brown, Penny J. Lewis   +3 more
doaj   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

FEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti, Ivano Eberini, Maria Luisa Genova, Francesca Mensitieri, Francesco Malatesta   +4 more
wiley   +1 more source

Flow of submitted research questions through the prioritisation process.

, 2016
Flow of submitted research questions through the prioritisation process.
Simon R. Knight (3239073), Graham W. Lipkin (3239058), Simon T. Ball (165346), Keith Hodkinson (3239061), Leanne Metcalfe (3239076), William Beale (3239049), Peter J. Morris (22944), Angela Beale (3239070), Fiona Loud (3239064), Lorna P. Marson (3239067), Katriona O’Donoghue (3239055), Rachel Hilton (3239052)   +11 more
core   +1 more source