Results 171 to 180 of about 372,499 (281)

Exploring the strengths and limitations of AI-driven variant prioritization versus manual curation in inborn errors of immunity. [PDF]

Front Genet
Moushib LI, Moreno-Ruiz N, Martín-Nalda A, Rivière JG, Urban B, Dieli-Crimi R, Perurena-Prieto J, Aguiló-Cucurull A, Pérez-Estévez E, Solanich X, Soler-Palacín P, Colobran R, Batlle-Masó L.   +12 more
europepmc   +1 more source

Prioritizing personalized medicine [PDF]

Genetics Research, 2014
openaire   +2 more sources

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Prioritization of zoonotic diseases in Bhutan through a One Health framework. [PDF]

One Health Outlook
Penjor K, Dahal N, Tshering U, Dorji C, Lungten L, Badhur J, Yangzom D, Dorjee S, Dukpa K, Wangdi K, Aye YM, Tenzin T.   +11 more
europepmc   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Waiting times for health services, health, and labour market outcomes. [PDF]

Eur J Public Health
Siciliani L.
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

From prioritization to implementation: updating the PARC WP5 project portfolio through the second prioritization round. [PDF]

Front Toxicol
Garcia Arenas C, Aiello Holden K, Svingen T, Knapen D, Kerdine-Römer S, Lindeman B, Smith NM, Le Hegarat L, Vanhaecke T, Rivière G, Marx-Stoelting P.   +10 more
europepmc   +1 more source

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Reward-based prioritization in working memory is distinct from recency and due to a resource trade-off. [PDF]

Psychon Bull Rev
Ricker TJ, Cagna CJ, Tong TT, Dobryakova E, Sandry J.   +4 more
europepmc   +1 more source