Results 61 to 70 of about 372,499 (281)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

What are the public health implications of the life course perspective?

Global Health Action, 2019
During the past decades innovative research has shown that exposure to harmful events during pregnancy and early infancy (‘the first 1000 days’) has an impact on health at subsequent stages of the life course and even across generations.
Jens Aagaard-Hansen, Shane A. Norris, Helle Terkildsen Maindal, Mark Hanson, Caroline Fall   +4 more
doaj   +1 more source

Adaptive Asset Management for Flood Protection: The FAIR Framework in Action

Infrastructures, 2020
Uncertainties about climate change consequences, changing societal requirements and system complexity require flood protection asset managers to continuously evaluate their asset management policies and practice to manage risk and improve the resilience ...
Bart Vonk, Wouter Jan Klerk, Peter Fröhle, Berry Gersonius, Frank den Heijer, Philipp Jordan, Ulf Radu Ciocan, Jeroen Rijke, Paul Sayers, Richard Ashley   +9 more
doaj   +1 more source

The Effect of Cognitive Task, Gait Speed, and Age on Cognitive–Motor Interference during Walking

Sensors, 2023
Dual-tasking can cause cognitive–motor interference (CMI) and affect task performance. This study investigated the effects of age, gait speed, and type of cognitive task on CMI during gait.
Jessica Pitts, Kunal Singhal, Yashashree Apte, Prakruti Patel, Lakshmi Kannan, Tanvi Bhatt   +5 more
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Prioritering

Socialmedicinsk tidskrift, 1992
Politik är att välja något framför något annat, konstaterar Peter F Hjort i sin artikel i detta nummer. På vissa områden betingas sådana val tydligt av olika värderingar tex på preven­tionens fält något som illustreras av artiklarna inom huvudtemat i detta nummer.
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Predominance Preferential Selection for Minimizing Surplus Parts in the Selective Assembly of a Flow Production System

Applied Sciences
This paper presents the Predominance Preferential Selection (PPS) algorithm, an advanced approach to optimizing selective assembly in flow production systems.
Kanghyeon Shin, Hyobin Son, Kyohong Jin
doaj   +1 more source

Workforce Innovation and Opportunity Act (WIOA) of 2014: A Preliminary Analysis [PDF]

, 2014
A preliminary analysis of provisions contained in the Workforce Innovation and Opportunity Act (WIOA) of 2014 related to employment, training, education, supports, and prioritization of workforce services for adults and youth with barriers to ...
Melissa Young
core  

Species prioritization for monitoring and management in regional multiple species conservation plans. [PDF]

, 2008
Successful conservation plans are not solely achieved by acquiring optimally designed reserves. Ongoing monitoring and management of the biodiversity in those reserves is an equally important, but often neglected or poorly executed, part of the ...
Andelman, Andelman, Andelman, Atkinson, Barrows, Canterbury, Carroll, Committee of Scientists, Cowling, Field, Field, Groves, Haight, Harding, Hauser, Hilty, Holthausen, Hoyer, Knight, Kremen, Lambeck, Lindenmeyer, Lindenmeyer, Margules, Markovchick-Nicholls, Moffett, National Research Council, Nicholson, Niemi, Noon, Noon, Noon, Noss, Olsen, Pearson, Possingham, Pressey, Purvis, Rahn, Rubinoff, Salafsky, Salafsky, Salzer, Simberloff, Smallwood, Stein, Stem, Tennant, The Nature Conservancy, Unitt, Wilhere, Wilson, Wilson, Yoccoz   +53 more
core   +1 more source