Results 121 to 130 of about 1,157,980 (306)
APPLICATION OF CDIO APPROACH TO MSC AND PHD ENGINEERING PROGRAMS
Высшее образование в России, 2017 The paper presents two-level lists of intended learning outcomes in the MSc’s programs (FCDI Syllabus v1) and PhD programs (FFCD Syllabus v1) on the analogy with the CDIO Syllabus v2 for graduates of basic engineering education programs based on the ...
A. I. Chuchalin, N. V. Daneikina
doaj
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
VaccinesBackground: Vaccination is one of the most effective measures to prevent influenza illness and its complications. Since the 1980s, countries and territories in the Americas have progressively implemented influenza vaccination operations in high-risk ...
Francisco Nogareda +18 more
doaj +1 more source
Efficient implementation of real-time programs under the VAX/VMS operating system [PDF]
Techniques for writing efficient real-time programs under the VAX/VMS oprating system are presented. Basic operations are presented for executing at real-time priority and for avoiding needlless processing delays.
Johnson, S. C.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cultural Summit II Work Book [PDF]
, 2014 OklahomaFeasibility study sInstitute of Museum and Library ...
Oklahoma Cultural Heritage Trust, Oklahoma Department of Libraries
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Assessing pathogen risk for wild bumblebees (Bombus spp., Apidae) in Canada
Conservation Science and PracticePathogen spillover has been cited as a threat to wild pollinator species, including bumblebees (Bombus spp). Conservation planning to conserve declining pollinators requires prioritization of at‐risk populations where threats might be particularly high ...
Amanda R. Liczner +2 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source