Results 261 to 270 of about 203,920 (318)

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter   +5 more
wiley   +1 more source

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Ion‑Mediated Structural Engineering of Hydrogel Interfaces for Tunable Mechanical and Analyte Diffusion Properties in Electrochemical Biosensors

open access: yesAdvanced Materials, EarlyView.
An ion‐mediated structural engineering strategy enables versatile modulation of PVA–Alginate hydrogel microstructure. We systematically examine how different ion combinations affect hydrogel mechanical properties and analyte diffusivity. Applying this novel strategy to hydrogel as the outer membrane in an electrochemical glucose biosensor allows ...
Dongwook Lee   +14 more
wiley   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

open access: yesAdvanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim   +9 more
wiley   +1 more source
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Prism Adaptation in M1

Journal of Cognitive Neuroscience, 2021
During prism adaptation (PA), active exposure to an optical shift results in sustained modifications of the sensorimotor system, which have been shown to expand to the cognitive level and serve as a rehabilitation technique for spatial cognition disorders. Several models based on evidence from clinical and neuroimaging studies offered a description of
Panico F.   +3 more
openaire   +4 more sources

Attention and prism adaptation

Cognitive Psychology, 1985
Abstract For both lateral displacement and rotation of the visual field, visual adaptation was reduced when subjects were required to perform a secondary cognitive task simultaneously with the primary exposure task of walking about hallways. Interference appeared to be independent of walking rate and occurred when the cognitive task was either mental
G M, Redding, S E, Clark, B, Wallace
openaire   +2 more sources

Prism adaptation in schizophrenia

Brain and Cognition, 2006
The prism adaptation test examines procedural learning (PL) in which performance facilitation occurs with practice on tasks without the need for conscious awareness. Dynamic interactions between frontostriatal cortices, basal ganglia, and the cerebellum have been shown to play key roles in PL.
Nirav O, Bigelow   +5 more
openaire   +2 more sources

Prism adaptation and brain damage

Neuropsychologia, 1972
Abstract Brain damaged (BD), psychiatric (P), and normal (N) groups were compared on adaptability to prism-displaced vision. Although no difference among the groups was found on compensatory pre-post shifts of felt limb position (“proprioceptive shift”), the BD group manifested significantly less shift in target-pointing accuracy (“negative ...
R B, Welch, G, Goldstein
openaire   +2 more sources

ADAPTATION TO PRISM-INDUCED HETEROPHORIA

Optometry and Vision Science, 1980
Measurements of the way the oculomotor system adapts to prism-induced heterophorias have been made in eight normal subjects. Adaptation to 2 delta vertically and, on separate occasions, to 6 delta horizontally was found to be substantially completed after only 2-3 minutes of binocular visual experience.
D B, Henson, R, North
openaire   +2 more sources

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