Results 81 to 90 of about 1,389,827 (273)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

The effect of different reaching interval on the course of prism adaptation [PDF]

open access: yes
Quick, accurate and precise reaching to a visual target is considered to be acquired by visuomotor learning or adaptation, during which both visual and proprioceptive feedback is required.
Takahiro HORAGUCHI, Saki AMANO
core   +2 more sources

On the Mechanics of Immediate Corrections and Aftereffects in Prism Adaptation

open access: yesVision, 2017
Prisms laterally shifting the perceived visual world cause arm movements to deviate from intended targets. The resulting error—the direct effect—both for pointing and throwing movements, usually corresponds to only around half of the prism’s optical ...
Klaudia Pochopien   +3 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

PRISM ADAPTATION: EFFECTS OF TARGET-TYPE AND PERFORMANCE FEEDBACK

open access: yes, 2011
When wearing prism goggles that displace vision laterally, the initial pointing errors are rapidly corrected. When the goggles are removed after a sufficient period of prism adaptation (PA), there is an aftereffect in spatial responding in the opposite ...
Ryan, Matthew P.
core  

Quantifying the Effectiveness of Prism Adaptation as Treatment for Unilateral Spatial Neglect

open access: yes, 2023
An Inclusive Meta-Analysis on the Effectiveness of Prism Adaptation as Treatment for Unilateral Spatial ...
Janet Bultitude   +4 more
core   +3 more sources

Multisensory and Modality-Specific Influences on Adaptation to Optical Prisms

open access: yesFrontiers in Human Neuroscience, 2017
Visuo-motor adaptation to optical prisms displacing the visual scene (prism adaptation, PA) is a method used for investigating visuo-motor plasticity in healthy individuals and, in clinical settings, for the rehabilitation of unilateral spatial neglect ...
Elena Calzolari   +6 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy