Results 141 to 150 of about 281,192 (235)

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

Housing Warmth/Coolness and Quietness Correlate With Whole‐Brain Fractional Anisotropy in Healthy Adults

Brain Health, EarlyView.
ABSTRACT Introduction Residential environments have been linked to brain structure, particularly in children, older adults, and clinical populations. However, little is known about how different dimensions of the housing environment relate to brain white matter microstructure in healthy adults, or whether specific environmental factors show stronger ...
Keisuke Kokubun, Kiyotaka Nemoto, Toshiharu Ikaga, Yoshinori Yamakawa   +3 more
wiley   +1 more source

Efficacy and Safety of Acupuncture-Related Therapies for Central Post-Stroke Pain: An Umbrella Review. [PDF]

J Pain Res
Wang L, Dou J, Yang Y, Qin D, Yu B, Li X, Ying J, Zhu L, Jiang N, Zhou Y, Zhao L, Zhou X, Gou C.   +12 more
europepmc   +1 more source

The influence of rivers on seabird foraging ecology

Biological Reviews, EarlyView.
ABSTRACT Rivers act as vital arteries to the world's oceans, delivering fresh water and nutrients that sustain marine ecosystems. Globally, river flow increasingly is being altered by climate change and anthropogenic pressures; yet the significance of rivers to predatory marine species, such as seabirds, and the extent to which river‐related changes ...
Julia B. Morais, Andre Chiaradia, Richard D. Reina   +2 more
wiley   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Obstructive Sleep Apnea and Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Observational Studies. [PDF]

J Clin Med
Vega Sanchez M, Córdova F, Mosquera Cisneros V, Rodríguez Tates M, Chauca Bajaña L, Quiguango Farias D, Flores Araque M, Velasquez Ron B.   +7 more
europepmc   +1 more source

Fear of grazing rivals the toxin‐inducing effects of nutrients in two marine harmful algae – a meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT One of the major subfields of chemical ecology is the study of toxins and how they mediate interactions between organisms. Toxins produced by harmful algae (phycotoxins) impact a wide variety of organisms connected to the marine food web. Significant research efforts have thus aimed to identify the ecological and evolutionary drivers behind ...
Milad Pourdanandeh, Erik Selander
wiley   +1 more source

The evidence base for ranger patrol effectiveness in conservation and how to improve it

Biological Reviews, EarlyView.
ABSTRACT Ranger patrols are a cornerstone of wildlife protection efforts around the world and occur across all ecological governance systems. Evidence that patrols reduce threats to wildlife and enable their recovery has not been systematically examined previously.
Trina Rytwinski, Robert S. A. Pickles, Matthew J. Muir, Steven J. Cooke, Joseph R. Bennett, Lisa A. Kelly, Adrienne Smith, Cynthia Cadet, Dwi N. Adhiasto, Inés Arroyo Quiroz, Mark D. Booton, Daphne P. Carlson, Drew T. Cronin, Anthony Dancer, Meredith L. Gore, Jennifer R. B. Miller, Stephen F. Pires, Amy Pokempner, James Slade, Andrew M. Lemieux   +19 more
wiley   +1 more source

Mapping the evidence on post-intensive care syndrome in paediatric populations: A scoping review protocol. [PDF]

PLoS One
Hassan S, Hassan A.
europepmc   +1 more source

Strategic Innovation for Sustainability: A Conceptual Model Linking Digitalization, Social Dynamics, and Climate Change Mitigation

Business Strategy and the Environment, EarlyView.
ABSTRACT This study addresses a significant research gap in the literature by systematically reviewing and synthesizing the interplay between social dynamics, environmental changes, and organizational innovation. Although prior research has explored these dimensions in isolation, the integrative framework remains lacking.
Gagan Deep Sharma, Sascha Kraus, Ritika Chopra, Dhairya Dev, Alberto Ferraris   +4 more
wiley   +1 more source