Results 41 to 50 of about 543,621 (317)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A Multi-Component Analysis of CPTED in the Cyberspace Domain

Sensors, 2020
The visual fidelity of a virtual environment lacks the exceedingly complex layers from the physical world, but the continuous improvements of image rendering technology and computation powers have led to greater demands for virtual simulations. Our study
Jemin Justin Lee, Myong-Hyun Go, Yu-Kyung Kim, Minhee Joo, JeongEun Seo, Haengrok Oh, Janghyuk Kauh, Kyungho Lee   +7 more
doaj   +1 more source

Single trace side-channel attack on key reconciliation in quantum key distribution system and its efficient countermeasures

ICT Express, 2021
Although quantum mechanics guarantees the security of the quantum key distribution system, it is crucial to examine whether the implementation flaws can lead to the disclosure of sensitive information. In this paper, we propose the side-channel attack on
Dongjun Park, GyuSang Kim, Donghoe Heo, Suhri Kim, HeeSeok Kim, Seokhie Hong   +5 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Practical solutions in fully homomorphic encryption: a survey analyzing existing acceleration methods

Cybersecurity
Fully homomorphic encryption (FHE) has experienced significant development and continuous breakthroughs in theory, enabling its widespread application in various fields, like outsourcing computation and secure multi-party computing, in order to preserve ...
Yanwei Gong, Xiaolin Chang, Jelena Mišić, Vojislav B. Mišić, Jianhua Wang, Haoran Zhu   +5 more
doaj   +1 more source

On the Evaluation of Privacy Impact Assessment and Privacy Risk Assessment Methodologies: A Systematic Literature Review

IEEE Access
Assessing privacy risks and incorporating privacy measures from the onset requires a comprehensive understanding of potential impacts on data subjects. Privacy Impact Assessments (PIAs) offer a systematic methodology for such purposes, which are closely ...
Samuel Wairimu, Leonardo Horn Iwaya, Lothar Fritsch, Stefan Lindskog   +3 more
doaj   +1 more source

Dependability Analysis of 5G-AKA Authentication Service From Server and User Perspectives

IEEE Access, 2020
The fifth generation (5G) technology offers a set of security services in order to provide secure communication to a large number of various devices. 5G Authentication and Key Agreement (5G-AKA) authentication service acts as the first step of securing ...
Lili Jiang, Xiaolin Chang, Jing Bai, Jelena Misic, Vojislav Misic, Zhi Chen   +5 more
doaj   +1 more source

Privacy-preserving federated genome-wide association studies via dynamic sampling [PDF]

, 2023
Xinyue Wang, Leonard Dervishi, Wentao Li, Erman Ayday, Xiaoqian Jiang, Jaideep Vaidya   +5 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source