Drug Repurposing for Treating NCOR‐Related Intellectual Disability
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong +15 more
wiley +1 more source
A blockchain-based verifiable CP-ABE scheme for medical data privacy protection. [PDF]
Zhao L, Dong G, Yuan H.
europepmc +1 more source
Excitation‐Selective Hydrochromic Upconversion in Zero‐Dimensional Metal Halides
Excitation wavelength dictates whether moisture speaks. In zero‐dimensional metal halides, the same humidity leaves the upconversion emission unchanged under 980 nm excitation yet triggers a distinct green‐to‐red shift under 1550 nm. This excitation‐selective hydrochromism, governed by the absorption at each wavelength, enables stimulus‐dependent ...
Joo Hyeong Han +6 more
wiley +1 more source
Privacy Protection in AI Transformation Environments: Focusing on Integrated Log System and AHP Scenario Prioritization. [PDF]
Lim DS, Lee SJ.
europepmc +1 more source
Atomically precise nanoclusters of Au/Ag alloys are explored as high‐performance photothermal materials, delivering record‐high photothermal efficiencies (up to 91%). Photo‐thermo‐electricity is further demonstrated by integrating nanocluster films with thermoelectric devices.
Avirup Sardar +7 more
wiley +1 more source
Privacy paradox and privacy calculus: the dilemma and trade-offs of privacy protection among Chinese middle-aged and elderly under digital stress. [PDF]
Hao J, Pulido CM, Song Y.
europepmc +1 more source
Nonlinear Ion‐Specific Control of Underwater Adhesion by Bottlebrush Polymer Interfaces
The efficiency of underwater adhesion is modulated by ion‐specific effects. Strongly hydrated Na+ remains separated from the mica surface by its hydration shell, preserving access to binding sites, whereas weakly hydrated K+ can partially dehydrate and occupy ditrigonal cavities.
Chang‐Sheng Wang +10 more
wiley +1 more source
A certificateless aggregate signature scheme for VANETs with privacy protection properties. [PDF]
Li H, Shen C, Huang H, Wu C.
europepmc +1 more source
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu +13 more
wiley +1 more source
Mediating effect of moral sensitivity in the relationship between mental workload and patient privacy protection among operating room nurses in China: a cross-sectional study. [PDF]
Tan R +6 more
europepmc +1 more source

