Results 271 to 280 of about 643,939 (333)

Bio‐Inspired Stored Magnetic Energy Actuator with Transient Triggering and Programmable Logic

open access: yesAdvanced Science, EarlyView.
A bio‐inspired magnetic energy actuator achieves 1.6 m/s transient release—three orders faster than conventional systems—via direct ink writing printed NdFeB/Polydimethylsiloxane composites and environmental locks; biomimetic AND‐gate logic enables sequential cue recognition (e.g., “temperature → rainfall”).
Chao Xu   +5 more
wiley   +1 more source

Hypoxia‐Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis

open access: yesAdvanced Science, EarlyView.
Hypoxia triggers lactylation of PRMT1 at K134/K145, enhancing its methyltransferase activity to asymmetrically dimethylate vimentin R64. This post‐translational cascade promotes vimentin filament assembly, cytoskeletal remodeling, and tumor metastasis, with PRMT1 inhibition (MS023) reducing metastatic colonization.
Jia Zhou   +16 more
wiley   +1 more source

SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang   +21 more
wiley   +1 more source

Middle Interlayer Engineered Ferroelectric NAND Flash Overcoming Reliability and Stability Bottlenecks for Next‐Generation High‐Density Storage Systems

open access: yesAdvanced Science, EarlyView.
A gate‐injection‐type Fe‐NAND architecture is developed by incorporating an Al2O3 middle interlayer to address key challenges in reliability and scalability. The engineered gate stack enables a wide memory window at low voltage, enhances retention beyond 10 years, suppresses disturbance and threshold voltage variability, and supports array‐level ...
Giuk Kim   +12 more
wiley   +1 more source

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