Results 41 to 50 of about 2,194 (257)

Towards Privacy-aware Software Reuse

Proceedings of the 7th International Conference on Model-Driven Engineering and Software Development, 2019
As software becomes more complex, reusing and integrating artifacts from existing projects that may be taken from open or organization-proprietary repositories is becoming an increasingly important practice. This practice requires an in-depth understanding of the projects to be reused and particularly their common and variable features and their non ...
Reinhartz-Berger, Iris, Zamansky, Anna, Koschmider, Agnes   +2 more
openaire   +2 more sources

PRESAGE: PRivacy-preserving gEnetic testing via SoftwAre Guard Extension

BMC Medical Genomics, 2017
Background Advances in DNA sequencing technologies have prompted a wide range of genomic applications to improve healthcare and facilitate biomedical research.
Feng Chen, Chenghong Wang, Wenrui Dai, Xiaoqian Jiang, Noman Mohammed, Md Momin Al Aziz, Md Nazmus Sadat, Cenk Sahinalp, Kristin Lauter, Shuang Wang   +9 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Principles for privacy protection software [PDF]

Proceedings of the tenth conference on Computers, freedom and privacy: challenging the assumptions, 2000
The privacy impact of computer systems is clearly a hot topic in the mainstream press [10] and the research world [1]. Experience with systems that protect privacy and others that violate it provides an opportunity to evaluate issues raised by current tools and proposed designs. Study of the strengths and shortcomings of existing tools can help clarify
openaire   +1 more source

Reusable Elements for the Systematic Design of Privacy-Friendly Information Systems: A Mapping Study

IEEE Access, 2019
Privacy by design is a new paradigm that promotes embedding privacy considerations throughout the development of information systems, to protect user privacy. Privacy engineering is the nascent field of research and practice that aims to realize this new
Julio C. Caiza, Yod-Samuel Martin, Danny S. Guaman, JOSE M. Del Alamo, Juan C. Yelmo   +4 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The Missing Link in Network Intrusion Detection: Taking AI/ML Research Efforts to Users

IEEE Access
Intrusion Detection Systems (IDS) tackle the challenging task of detecting network attacks as fast as possible. As this is getting more complex in modern enterprise networks, Artificial Intelligence (AI) and Machine Learning (ML) have gained substantial ...
Katharina Dietz, Michael Muhlhauser, Jochen Kogel, Stephan Schwinger, Marleen Sichermann, Michael Seufert, Dominik Herrmann, Tobias Hosfeld   +7 more
doaj   +1 more source

Speed Reading in the Dark: Accelerating Functional Encryption for Quadratic Functions with Reprogrammable Hardware

Transactions on Cryptographic Hardware and Embedded Systems, 2021
Functional encryption is a new paradigm for encryption where decryption does not give the entire plaintext but only some function of it. Functional encryption has great potential in privacy-enhancing technologies but suffers from excessive computational ...
Milad Bahadori, Kimmo Järvinen, Tilen Marc, Miha Stopar   +3 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source