Results 231 to 240 of about 3,049,776 (389)

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Transformative collaborations in a time of change: Europe's unique model for public-private-philanthropic partnerships. [PDF]

Lancet Reg Health Eur
Hurtado Del Pozo C, Blomberg N.
europepmc   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Utilisation of HIV pre-exposure prophylaxis and preferences of alternative long-acting modalities among men who have sex with men in Hong kong: a cross-sectional study. [PDF]

BMC Public Health
Kwan TH, Chan DPC, Lee SS.
europepmc   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

'She mustn't be the mother alone': motivators, barriers, and recommendations for men's engagement with reproductive research in South Africa. [PDF]

Health Promot Int
Gardiner CV, Headman T, Soepnel LM, Mabasa J, Klingberg S, Motlhatlhedi M, Pentecost M, Draper CE, Nyati LH.   +8 more
europepmc   +1 more source

Government partnerships with corporate virtual primary care. [PDF]

CMAJ
Salahub C, Hedden L, Kiran T, Lavergne MR, Spithoff S, Lapointe-Shaw L.   +5 more
europepmc   +1 more source

Caveat Partner: Reflections on Partnership with the Private Sector

, 1998
T. Hancock
semanticscholar   +1 more source

The Inaugural NIH‐Wide Strategic Plan for Autoimmune Disease Research (Fiscal Years 2026–2030)

Arthritis &Rheumatology, EarlyView.
Victoria K. Shanmugam, Carmen Ufret‐Vincenty, Xinrui Li, Janine A. Clayton   +3 more
wiley   +1 more source

AI voice journaling for future language teachers: A path to well‐being through reflective practices

British Educational Research Journal, EarlyView.
Abstract This study aimed to explore the perceived impact of using an AI‐powered voice journaling app in overcoming the challenges and stressors encountered by senior students enrolled in teaching practicum at an English Language Teaching Bachelor's programme.
Bora Demir, Duygu Özdemir
wiley   +1 more source