Results 61 to 70 of about 2,016,145 (275)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A realização do sujeito pronominal em Florianópolis

open access: yesWorking Papers em Linguística, 2014
Este artigo, de base teórica variacionista, discute a realização do sujeito – pleno ou nulo – na cidade de Florianópolis, mais precisamente na comunidade rural da Costa da Lagoa. A investigação do fenômeno é empreendida a partir de vasta bibliografia no
Diego Rafael Vogt, Bruno Cardoso
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A note on subject clitics in Akan

open access: yesStudies in African Linguistics, 1998
This paper is concerned with the analysis of pronominal subject clitics (SCLs) in Akan within the Priniciples and Parameters framework of syntactic theory.
Richard Campbell
doaj   +3 more sources

Pro-drop in Farsi: A Case Study of Bilingual Speakers

open access: yesKülönleges Bánásmód
This research is meant to uncover some of the internal grammatical structure of bilingual Farsi speakers who have English as their dominant language. Bilinguals, whose mother tongue is Farsi but whose dominant language is English, are influenced by their
Foroozan Hajian, Anikó Vargáné Nagy
doaj   +1 more source

A perda da reflexão como fator determinante no uso do pronome expresso sujeito em sentenças finitas no português brasileiro

open access: yesIdeação, 2000
O objetivo deste artigo é expor, introdutoriamente, a teoria de Princípios e Parâmetros (CHOMSKY, 1981) restringindo-se às características do conhecido e famoso parâmetro pro-drop.
Maridelma Laperuta
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Pro-drop and subject pronouns in Assamese

open access: yesInternational Journal of Linguistics, Literature and Translation, 2020
In recent years a considerable attention has been given to the study of control and pro-drop. Languages with rich agreement patterns allow for phonetically empty subject which is called “pro”. This paper deals with the pro-drop phenomena of Assamese.
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy