Results 91 to 100 of about 7,333,561 (296)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Contract farming and pro-environmental behavior: insights from beef cattle farmers

Frontiers in Sustainable Food Systems
IntroductionFacilitating and motivating farmers to adopt standardized pro-environmental production technologies serve as a solution to agricultural surface pollution.
Yuan Liang, Peihang Zhang, Wentai Bi, Qi Qi, Fengjie Xie   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Pro-environmental behaviors for thee but not for me: green giants, green Gods, and external environmental locus of control

, 2014
PRO-ENVIRONMENTAL BEHAVIORS FOR THEE BUT NOT FOR ME: GREEN GIANTS, GREEN GODS, AND EXTERNAL ENVIRONMENTAL LOCUS OF CONTROL Pro-environmental behaviors for thee but not for me: green giants, green Gods, and external environmental locus of control (-
Laroche, Michel, Cleveland, Mark, Kalamas, Maria   +2 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The impact of scientific consensus on pro-environmental diffusion behaviors

This study has two purposes, through online experimental manipulation, firstly we will test the causal relationship of perceived scientific consensus on pro-environmental diffusion behaviors. Secondly, we will further test the mediating role of diffusion
Nina He, JIE ZHANG
core   +2 more sources

Biophilia in Italian preschool children: preliminary findings

Frontiers in Psychology
This study investigated the relationship between biophilia, pro-environmental behaviors, and connectedness to nature in Italian preschool children. A total of 196 children (ages 24–65 months) and their parents participated.
Sabine Pirchio, Sara Costa, Rosa Ferri
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Stepping Outside the Self Promotes Pro-Environmental Behaviors

, 2018
Although different self-perspectives can prompt different mindsets, leading to different responses, little is known about how self-perspective impacts pro-environmental behaviors.
Emine Sarigöllü, Chenxuan Hou, Myung-Soo Jo, Dapeng Liang   +3 more
core   +1 more source