Results 141 to 150 of about 7,333,561 (296)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Understanding the Mediating Role of Eco-Anxiety in Promoting Pro-Environmental Behaviors Across Diverse Cultural Worldviews: a preliminary study

open access: yesJournal of Clinical & Developmental Psychology
Background: Eco-anxiety describes the emotional response to the impacts of climate change, with pro-environmental behaviors serving as an effective coping strategy.
Giulia Rocchi
doaj   +1 more source

Spillover effects of pro-environmental behavior in the Metaverse

open access: yesFrontiers in Psychology
Existing research has extensively explored the spillover effects of pro-environmental behavior. However, systematic research regarding the spillover effects and psychological mechanisms of pro-environmental behavior in the Metaverse remains scarce. This study investigates the spillover effects of pro-environmental behavior in the Metaverse on real ...
Wang, Xiaoming, Zhang, Keqin, Yu, Jie
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Urban Renewal and Transformation of Residents’ Pro-Environmental Behaviors: Evidence from the Renovation of Old Residential Areas in Chengdu, China

open access: yes
Based on research data from the renovation of old residential areas in Chengdu, China, this study provides empirical evidence regarding the causal relationship between urban renewal and the transformation of residents’ pro-environmental behaviors ...
Xingbang He, Jie Mao, Xiaoxia Ran
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Influential factors of residents’ online green behavior in China: the mediating role of social trust

open access: yesScientific Reports
Environmental issues are associated with the pursuit of sustainable development in human society. To address environmental challenges, it is crucial to encourage residents to engage in pro-environmental behaviors.
Yong Li, Xiao Yu, Ranran Wang
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

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