Results 71 to 80 of about 133,914 (295)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Individual and situational determinants of plastic waste sorting: an experience sampling method study protocol

open access: yesBMC Psychology, 2021
Background Plastic waste management is one of the most challenging problems of our time. Until now, only 9% of the produced plastics has been recycled.
Valérie J. V. Broers   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Linking energy behaviour, attitude and habits with environmental predisposition and knowledge

open access: yesInternational Journal of Sustainable Energy, 2017
The purpose of this paper is to present and discuss the findings of an empirical study that compares individuals' environmental predisposition and knowledge with their energy behaviour, attitude and habits.
Mary Pothitou   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Environmental considerations as a basis for employee pro-environmental behaviour

open access: yes, 2018
Organisations are increasingly recognising that environmental problems will reduce if their employees act more pro-environmentally. However, pro-environmental behaviour (at home or at work) generally implies a conflict between immediate gratifications or
Steg, Linda   +4 more
core   +1 more source

Associations between pro-environmental behaviour and neighbourhood nature, nature visit frequency and nature appreciation: Evidence from a nationally representative survey in England

open access: yesEnvironment International, 2020
Progress on changing human behaviour to meet the challenges of regional and global sustainability has been slow. Building on theory as well as small-scale survey and experimental evidence that exposure to nature may be associated with greater pro ...
Ian Alcock   +4 more
doaj   +1 more source

One for all doesn’t Work: Micromanaging Pro-environmental Behaviour

open access: yesJISR Management and Social Sciences & Economics, 2022
This study aims to identify the flaws in current theories and present reasons for their failure. Despite all the efforts, the adaptability of products with sustainability elements remains low.
Kashif  Riaz   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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