Results 71 to 80 of about 7,889,625 (287)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Background Plastic waste management is one of the most challenging problems of our time. Until now, only 9% of the produced plastics has been recycled.
Valérie J. V. Broers +5 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Linking energy behaviour, attitude and habits with environmental predisposition and knowledge
The purpose of this paper is to present and discuss the findings of an empirical study that compares individuals' environmental predisposition and knowledge with their energy behaviour, attitude and habits.
Mary Pothitou +3 more
doaj +1 more source
One for all doesn’t Work: Micromanaging Pro-environmental Behaviour
This study aims to identify the flaws in current theories and present reasons for their failure. Despite all the efforts, the adaptability of products with sustainability elements remains low.
Kashif Riaz +2 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A range of actors, including government, third sector organisations (TSOs) and academics, have claimed recently that third sector organisations (TSOs) can play an important role in supporting people to adopt pro-environmental behaviours.
Buchs, Milena +2 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Environmental considerations as a basis for employee pro-environmental behaviour
Organisations are increasingly recognising that environmental problems will reduce if their employees act more pro-environmentally. However, pro-environmental behaviour (at home or at work) generally implies a conflict between immediate gratifications or
Steg, Linda +4 more
core +1 more source

