Results 61 to 70 of about 67,015 (282)

Comparing public support for wildlife protection and climate protection

Envigogika, 2021
In this study we provide a detailed analysis and comparison of the public support for climate protection and wildlife protection using nationally representative data from the Czech Republic.
Jan Krajhanzl, Tomáš Chabada
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

An Empirical Comparison of Human Value Models

Frontiers in Psychology, 2018
Over the past century, various value models have been proposed. To determine which value model best predicts prosocial behavior, mental health, and pro-environmental behavior, we subjected seven value models to a hierarchical regression analysis.
Paul H. P. Hanel, Lukas F. Litzellachner, Gregory R. Maio   +2 more
doaj   +1 more source

The Strategy To Increase The Purchase Intention Of Unpacked Products

Jurnal Manajemen, 2023
Consumer orientation toward Green Products or environmentally friendly products is one of the supporting factors for business continuity. The Green Product in this study is a refill product without packaging (unpacked product).
Dipa Mulia, Muchsin S. Shihab
doaj   +1 more source

Explaining Personal and Public Pro-Environmental Behaviors

, 2023
A global crisis generated by human-made climate change has added urgency to the need to fully understand human pro-environmental behaviors (PEBs) that may help slow down the crisis. Factors influencing personal and public PEBs may or may not be the same.
Michaela LaNay Wilson, Philip Q. Yang
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The Role of Green HRM and Sustainability Orientation on Pro-Environmental Employees

West Science Business and Management
This study investigates the role of Green Human Resource Management (Green HRM) practices and Sustainability Orientation in fostering pro-environmental behavior among employees in Indonesia. Using a quantitative approach, data were collected from 140 respondents through a structured Likert-scale questionnaire (1-5) and analyzed with Structural Equation
Loso Judijanto, Mohammad Gifari Sono, Muhammad Abdul Rosid, Ilma Darojat, Adi Lukman Hakim   +4 more
openaire   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Relationships between value orientations, self-determined motivational types and pro-environmental behavioural intentions [PDF]

Journal of Environmental Psychology, 2010
We examined the predictive power of egoistic altruistic and biospheric value orientations and six types of self-determined motivations (i e intrinsic motivation integrated regulation identified regulation introjected regulation external regulation and amotivation) toward acting pro-environmentally for explaining two types of pro-environmental ...
de Groot, Judith M., Steg, Linda
openaire   +2 more sources