Results 61 to 70 of about 490,290 (287)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Towards resilience through systems-based plant breeding. A review [PDF]

open access: yes, 2018
How the growing world population can feed itself is a crucial, multi-dimensional problem that goes beyond sustainable development. Crop production will be affected by many changes in its climatic, agronomic, economic, and societal contexts.
Eekeren, Nick van   +3 more
core   +2 more sources

An Empirical Comparison of Human Value Models

open access: yesFrontiers in Psychology, 2018
Over the past century, various value models have been proposed. To determine which value model best predicts prosocial behavior, mental health, and pro-environmental behavior, we subjected seven value models to a hierarchical regression analysis.
Paul H. P. Hanel   +2 more
doaj   +1 more source

The Strategy To Increase The Purchase Intention Of Unpacked Products

open access: yesJurnal Manajemen, 2023
Consumer orientation toward Green Products or environmentally friendly products is one of the supporting factors for business continuity. The Green Product in this study is a refill product without packaging (unpacked product).
Dipa Mulia, Muchsin S. Shihab
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The Role of Green HRM and Sustainability Orientation on Pro-Environmental Employees

open access: yesWest Science Business and Management
This study investigates the role of Green Human Resource Management (Green HRM) practices and Sustainability Orientation in fostering pro-environmental behavior among employees in Indonesia. Using a quantitative approach, data were collected from 140 respondents through a structured Likert-scale questionnaire (1-5) and analyzed with Structural Equation
Loso Judijanto   +4 more
openaire   +1 more source

Ecological Belief in a Just World: A Cross-Validation Study in a Turkish Sample

open access: yesPsikoloji Çalışmaları, 2021
Examples of environmental injustice are widespread, and perceived injustice is an important predictor of environmental behaviour. However, the extent to which inequalities are perceived as just or unjust, as well as reactions towards the perception of ...
Gözde Kıral Uçar   +3 more
doaj   +1 more source

Responsible Research and Innovation between \u201cnew governance\u201d and fundamental rights [PDF]

open access: yes, 2018
This chapter frames RRI as an emerging governance approach in the EU regulatory context. We argue that reference to fundamental rights makes RRI a distinctive approach to responsibility compared to other existing paradigms and that human rights, in ...
Arnaldi, Simone   +2 more
core   +1 more source

Mediating Effect of Environmental Orientation on Pro-Environmental Purchase Intentions in a Low-Involvement Product Situation

open access: yesAustralasian Marketing Journal, 2017
Low-involvement consumption includes the majority of regular purchases by individuals and the community, and collectively these have a substantial negative environmental impact. It is, therefore, an important environmental domain to examine. This research surveys 340 Turkish consumers and examines whether apathy, locus of control and myopia influence ...
Coskun, Aysen   +2 more
openaire   +2 more sources

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