Results 261 to 270 of about 3,051,760 (306)
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Pro‐inflammatory cytokines in patients with essential hypertension
European Journal of Clinical Investigation, 2001BackgroundIt has been suggested that abnormalities in the immune response play a role in the pathogenesis of essential hypertension (EH). The aim of this study was to assess circulating concentrations and ex vivo production of the pro‐inflammatory cytokines tumour necrosis factor‐α(TNF‐α) and interleukin‐1β (IL‐1β), and of the anti‐inflammatory ...
Peeters, A.C.T.M. +5 more
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Pro-Inflammatory Cytokine Response in Acute Infection
2003The invasion of human beings or other multi-cellular organisms by micro-organisms usually leads to inflammation. Depending on the virulence of the micro-organism, the size of the inoculum, and the quality of the host’s defence mechanisms, the inflammatory response will be confined to the local site or may extend and involve the entire body.
Alisjahbana, B. +2 more
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The paradox of pro-inflammatory cytokines in cancer
Cancer and Metastasis Reviews, 2006Cytokines such as IL-1 and TNF are primarily pro-inflammatory. The inflammation induced by these cytokines is reflected in the type of genes they induce. In the pathogenesis of carcinogenesis as well as tumor growth and spread, cytokines such as IL-1 and TNF induce chemokines that attract neutrophils.
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Pro-Inflammatory Cytokines in Elective Flap Surgery
Journal of Surgical Research, 2007Surgical trauma releases inflammatory mediators such as pro-inflammatory cytokines. In this prospective, controlled, randomized trial we investigated the release of pro-inflammatory cytokines and monocyte/macrophage activation in patients scheduled for breast reconstruction after mastectomy.
Annette, Schmidt +3 more
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Regulation of Multidrug Resistance by Pro-Inflammatory Cytokines
Current Cancer Drug Targets, 2006Various mechanisms have been implicated in the development of resistance of cancer cells to chemotherapy. Multidrug resistance (MDR) is a phenomenon in which cancer cells are resistant to the cytotoxic effects of various structurally and mechanistically unrelated chemotherapeutic agents.
Emmanuel A, Ho +1 more
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Pro-inflammatory cytokines and their effects in the dentate gyrus
2007The older notion of a central nervous system existing in essential isolation from the immune system has changed dramatically in recent years as the body of evidence relating to the interactions between these two systems has grown. Here we address the role of a particular subset of immune modulatory molecules, the pro-inflammatory cytokines, in ...
Mark, Pickering, John J, O'Connor
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Airway nociceptors activated by pro-inflammatory cytokines
Respiratory Physiology & Neurobiology, 2007The present studies evaluate whether the vagus nerves link the lungs' immune and neural systems by transmitting information through pulmonary nociceptors. Single unit activities from pulmonary nociceptors [C fiber receptors (CFRs) and high threshold Adelta fiber receptors (HTARs)] were recorded from the cervical vagus nerve in anesthetized, open-chest,
Jerry, Yu +4 more
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Pro-inflammatory Cytokines and the Depressive Phenotype
2021In this review, the evidence is summarized implicating chronic low-grade inflammation in the pathophysiology of major depression. The possible mechanisms whereby such inflammatory changes lead to aberrant endocrine and neurotransmitter functions are also outlined and implicate the pro-inflammatory cytokines which are released from activated microglia ...
Feyza Aricioglu +2 more
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Pro-inflammatory Maternal Cytokine Profile in Preterm Delivery
Obstetrical & Gynecological Survey, 2003PROBLEM: The objective of this study was to determine the levels of cytokines produced by maternal peripheral blood mononuclear cells (PBMC) upon stimulation with a mitogen, with autologous placental cells and with a trophoblast antigen extract.METHOD OF STUDY: Peripheral blood mononuclear cells from 54 women with a history of successful pregnancy ...
M, Makhseed +5 more
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Pro‐Inflammatory Cytokines and the Marrow Microenvironment
The FASEB Journal, 2017In the presence of marrow, vasodilation of the femoral principal nutrient artery (PNA; the primary conduit for blood flow to long bone) was impaired in young ( p <0.05; Prisby et al., 2014, ASBMR) and old (p=0.07; Lee et al., 2014, ASBMR) rats.
Seungyong Lee, Rhonda Prisby
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