Results 61 to 70 of about 3,051,760 (306)

Pro-inflammatory and Anti-inflammatory Cytokines Profile in Celiac Disease Patients [PDF]

Journal of Bioscience and Applied Research
Celiac disease is an autoimmune disorder that occurs when people with a genetic predisposition react to gluten, a protein found in wheat, barley, and rye. This reaction primarily affects the small intestine, causing a variety of symptoms.
Zahraa Qasim, Hawraa Al-Dahhan
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Modulation of pro-inflammatory cytokines in normal and inflamed skin [PDF]

, 2001
This thesis describes the expression and modulation of pro-inflammatory cytokines in normal and inflamed skin. During the last few decades it has become clear that the skin comprises a complex network of interacting cells including keratinocytes (KC ...
Companjen, A.R. (Arjen), Companjen, AR (Arjen)   +1 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Role of pro-inflammatory cytokines in rheumatoid arthritis

Springer Seminars in Immunopathology, 1998
Rheumatoid arthritis (RA) is well known to be a chronic autoimmune/inflammatory disease which leads to progressive joint damage and destruction. Less well known is the fact that in severe cases of RA, with extra-articular manifestations and multiple joint involvement, there is also a significant reduction in life expectancy [28]. Hence the need for new
Brennan, F, Maini, R, Feldmann, M
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Genetic Defects and Pro-inflammatory Cytokines in Parkinson's Disease

Frontiers in Neurology, 2021
Parkinson's disease (PD) is a movement disorder attributed to the loss of dopaminergic (DA) neurons mainly in the substantia nigra pars compacta. Motor symptoms include resting tremor, rigidity, and bradykinesias, while non-motor symptoms include ...
Albert Frank Magnusen, Shelby Loraine Hatton, Reena Rani, Manoj Kumar Pandey, Manoj Kumar Pandey   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Status of Pro-inflammatory cytokines in infertile and non-infertile cohorts.

, 2023
Status of Pro-inflammatory cytokines in infertile and non-infertile cohorts.
Mbah Ntepe Leonel Javeres (15198350), Faheem Tahir (10358665), Syed Muhammad Nurulain (15198353), Syed Tahir Abbas Shah (14074194), Rabia Habib (761308), Sabir Hussain (1332675), Zahid Muneer (606786), Khulah Sadia (15198347)   +7 more
core   +1 more source

Increased plasma levels of mitochondrial DNA and pro-inflammatory cytokines in patients with progressive multiple sclerosis [PDF]

, 2020
The role of damage-associated molecular patterns in multiple sclerosis (MS) is under investigation. Here, we studied the contribution of circulating high mobility group box protein 1 (HMGB1) and mitochondrial DNA (mtDNA) to neuroinflammation in ...
Sola P., Neroni A., Mattioli, Marco, Bianchini E., Pinti M., De Biasi S., Nasi M., Iannone A., Ferraro D., Simone A. M., Vitetta F., Cossarizza A., Gibellini L., Mattioli A. V.   +13 more
core   +1 more source