Results 221 to 230 of about 2,741,379 (327)

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

Advanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng, Xuegang Wang, Mingjun Zhong, Jia Geng, Wenjian Li, Kanglu Pei, Jing Wang, Lanchen Wang, Yu Lu, Jing Cheng, Fengxiao Bu, Huijun Yuan   +11 more
wiley   +1 more source

Towards Automatic Expressive Pipa Music Transcription Using Morphological Analysis of Photoelectric Signals. [PDF]

Sensors (Basel)
Wang Y, Li X, Zhang Y, Wang Q.
europepmc   +1 more source

Dynamics of Cell Fate Decisions during Chemically Induced Multi‐Lineage Trans‐Differentiation at Single‐Cell Level

Advanced Science, EarlyView.
A critical aspect of chromosomal remodeling in small molecule‐induced multilineage trans‐differentiation(iMT) is elucidated. A dynamic atlas spanning over 35 days profiles terminal trans‐differentiated cells, which reverted to a more youthful state. This study reveals parallels between iMT and other cell fate determination processes, emphasizing an ...
Weigao E, Lijiang Fei, Jingjing Wang, Xinru Wang, Renying Wang, Xueyi Wang, Peijing Zhang, Jianhui Chen, Junqing Wu, Mengmeng Jiang, Daosheng Huang, Danmei Jia, Guoji Guo, Xiaoping Han   +13 more
wiley   +1 more source

Research on the connectivity reliability analysis and optimization of natural gas pipeline network based on topology. [PDF]

Sci Rep
Yang X, Chen K, Liu M.
europepmc   +1 more source

A Multi‐Objective Molecular Generation Method Based on Pareto Algorithm and Monte Carlo Tree Search

Advanced Science, EarlyView.
Pareto Monte Carlo Tree Search Molecular Generation (PMMG), a molecular generation approach leveraging Monte Carlo Tree Search (MCTS) and Pareto algorithm, efficiently explores the Pareto front in high‐dimensional objective spaces for multi‐objective drug design.
Yifei Liu, Yiheng Zhu, Jike Wang, Renling Hu, Chao Shen, Wanglin Qu, Gaoang Wang, Qun Su, Yuchen Zhu, Yu Kang, Peichen Pan, Chang‐Yu Hsieh, Tingjun Hou   +12 more
wiley   +1 more source

Enabling disaggregation of Asian American subgroups: a dataset of Wikidata names for disparity estimation. [PDF]

Sci Data
Lin Q, Ouyang D, Guage C, Gallegos IO, Goldin J, Ho DE.   +5 more
europepmc   +1 more source

β‐Glucuronidase‐Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool

Advanced Science, EarlyView.
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue, Ruiyang Gao, Ling Zhao, Donghui Liu, Cheng Lv, Ziyi Wang, Fangbin Ai, Beibei Zhang, Zhilun Yu, Xiaolong Geng, Hao Wang, Kang Wang, Kaixian Chen, Chenghai Liu, Zhengtao Wang, Wei Dou   +15 more
wiley   +1 more source

Quick mining in dense data: applying probabilistic support prediction in depth-first order. [PDF]

PeerJ Comput Sci
Sadeequllah M, Rauf A, Rehman SU, Alnazzawi N.   +3 more
europepmc   +1 more source

Structural Diversity of Mitochondria in the Neuromuscular System across Development Revealed by 3D Electron Microscopy

Advanced Science, EarlyView.
Mitochondria across the entire neuromuscular system have been comprehensively reconstructed at different developmental stages using 3D electron microscopy. Fundamental structural principles related to synaptic function are preserved across development, and these morphologies are adapted to ensure effective neural circuit function.
J. Alexander Bae, Myung‐kyu Choi, Soungyub Ahn, Gwanho Ko, Daniel T. Choe, Hyunsoo Yim, Ken C. Nguyen, Jinseop S. Kim, David H. Hall, Junho Lee   +9 more
wiley   +1 more source

Hybrid Machine Learning-Based Fault-Tolerant Sensor Data Fusion and Anomaly Detection for Fire Risk Mitigation in IIoT Environment. [PDF]

Sensors (Basel)
Desikan J, Singh SK, Jayanthiladevi A, Bhushan S, Rishiwal V, Kumar M.   +5 more
europepmc   +1 more source