Results 51 to 60 of about 151,404 (250)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Underwater Network Time Synchronization Method Based on Probabilistic Graphical Models

Journal of Marine Science and Engineering
In underwater clustering and benchmark networks, nodes need to reduce the rate and energy consumption of acoustic communication while ensuring synchronization accuracy.
Yujie Ouyang, Yunfeng Han, Zeyu Wang, Yifei He   +3 more
doaj   +1 more source

High-dimensional Data Publication Under Local Differential Privacy [PDF]

Jisuanji kexue
With the increasing availability of high-dimensional data collected from numerous users,preserving user privacy while utilizing high-dimensional data poses significant challenges.This paper focuses on the problem of high-dimensional data publication ...
CAI Mengnan, SHEN Guohua, HUANG Zhiqiu, YANG Yang
doaj   +1 more source

Yes we care!-Certification for machine learning methods through the care label framework

Frontiers in Artificial Intelligence, 2022
Machine learning applications have become ubiquitous. Their applications range from embedded control in production machines over process optimization in diverse areas (e.g., traffic, finance, sciences) to direct user interactions like advertising and ...
Katharina J. Morik, Helena Kotthaus, Raphael Fischer, Sascha Mücke, Matthias Jakobs, Nico Piatkowski, Andreas Pauly, Lukas Heppe, Danny Heinrich   +8 more
doaj   +1 more source

Context-Aware Recursive Bayesian Graph Traversal in BCIs

, 2017
Noninvasive brain computer interfaces (BCI), and more specifically Electroencephalography (EEG) based systems for intent detection need to compensate for the low signal to noise ratio of EEG signals.
Erdogmus, Deniz, Haghighi, Marzieh, Moghadamfalahi, Mohammad, Nezamfar, Hooman, Salehi, Seyed Sadegh Mohseni   +4 more
core   +1 more source

Probabilistic graphical models for genetic association studies [PDF]

Briefings in Bioinformatics, 2011
Probabilistic graphical models have been widely recognized as a powerful formalism in the bioinformatics field, especially in gene expression studies and linkage analysis. Although less well known in association genetics, many successful methods have recently emerged to dissect the genetic architecture of complex diseases.
Mourad, Raphaël, Sinoquet, Christine, Leray, Philippe   +2 more
openaire   +3 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Modelling structured data with Probabilistic Graphical Models [PDF]

EAS Publications Series, 2016
Most clustering and classification methods are based on the assumption that the objects to be clustered are independent. However, in more and more modern applications, data are structured in a way that makes this assumption not realistic and potentially misleading.
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source