Results 51 to 60 of about 152,362 (267)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
High-dimensional Data Publication Under Local Differential Privacy [PDF]
Jisuanji kexueWith the increasing availability of high-dimensional data collected from numerous users,preserving user privacy while utilizing high-dimensional data poses significant challenges.This paper focuses on the problem of high-dimensional data publication ...
CAI Mengnan, SHEN Guohua, HUANG Zhiqiu, YANG Yang
doaj +1 more source
Parametric Modelling of Multivariate Count Data Using Probabilistic Graphical Models [PDF]
, 2013 Multivariate count data are defined as the number of items of different categories issued from sampling within a population, which individuals are grouped into categories.
Durand, Jean-Baptiste +2 more
core +2 more sources
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Statistical inference with probabilistic graphical models
CoRR, 2014 Chapter of "Statistical Physics, Optimization, Inference, and Message-Passing Algorithms", Eds.: F. Krzakala, F. Ricci-Tersenghi, L. Zdeborova, R. Zecchina, E. W. Tramel, L. F. Cugliandolo (Oxford University Press, to appear)
Angélique Dremeau +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Markov Properties for Graphical Models with Cycles and Latent Variables [PDF]
, 2017 We investigate probabilistic graphical models that allow for both cycles and latent variables. For this we introduce directed graphs with hyperedges (HEDGes), generalizing and combining both marginalized directed acyclic graphs (mDAGs) that can model ...
Forré, Patrick, Mooij, Joris M.
core +1 more source
Context-Aware Recursive Bayesian Graph Traversal in BCIs
, 2017 Noninvasive brain computer interfaces (BCI), and more specifically Electroencephalography (EEG) based systems for intent detection need to compensate for the low signal to noise ratio of EEG signals.
Erdogmus, Deniz +4 more
core +1 more source
An Introduction to Probabilistic Graphical Models
, 2002 In this chapter we will introduce two probabilistic graphical models -Bayesian networks and Gaussian networks- that will be used to carryout factorization of the probability distribution of the selected individuals in the Estimation of Distribution Algorithms based approaches.
openaire +2 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source