Results 111 to 120 of about 224,550 (312)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Interlayer Dzyaloshinskii–Moriya Interaction in Synthetic Ferrimagnets for Spiking Neural Networks

Advanced Science, EarlyView.
This work introduces a groundbreaking integration of asymmetric magnetic structures (synthetic ferrimagnets) and antisymmetric magnetic interaction (interlayer Dzyaloshinskii–Moriya interaction) for the first time. It addresses the critical challenge of IL‐DMI detection and shows the discovery of unprecedented analog‐like spin‐orbit torque switching ...
Shen Li, Xing Chen, Mouad Fattouhi, Tianxun Huang, Chen Lv, Mark C. H. de Jong, Pingzhi Li, Daoqian Zhu, Xiaoyang Lin, Felipe Garcia‐Sanchez, Eduardo Martinez, Stéphane Mangin, Bert Koopmans, Weisheng Zhao, Reinoud Lavrijsen   +14 more
wiley   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

Non‐Volatile Phase Modulation with Ultralow Energy Consumption Enabled by 2D Ferroelectric/TMD Heterostructures

Advanced Science, EarlyView.
We demonstrate a hybrid WS2/CuInP2S6/graphene heterostructure integrated on a silicon nitride microring resonator for non‐volatile optical phase modulation with ultra‐low energy consumption and low insertion loss. While CIPS alone does not provide efficient optical index modulation, the engineered proposed device structure converts ferroelctric domain ...
Lalit Singh, Shi Guo, Yuhui Yang, Sholehin Juperi, Rui Yu, Xiangxin Gong, Jeremy Leong, Sung‐Gyu Lee, Qingyun Wu, Lay Kee Ang, Sang Hoon Chae   +10 more
wiley   +1 more source

Probabilistic Inductive Logic Programming Based on Answer Set Programming [PDF]

, 2014
Matthias Nickles, Alessandra Mileo
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Symbolic Exact Inference for Discrete Probabilistic Programs

, 2019
The computational burden of probabilistic inference remains a hurdle for applying probabilistic programming languages to practical problems of interest.
Broeck, Guy Van den, Holtzen, Steven, Millstein, Todd   +2 more
core  

Modeling PU learning using probabilistic logic programming [PDF]

, 2023
Victor Verreet, Luc De Raedt, Jessa Bekker   +2 more
openalex   +1 more source

Ubiquitination‐Driven Reprogramming of Proteostasis in Metastasis

Advanced Science, EarlyView.
The DCAF12–TRiC/CCT axis is a key regulator of metastasis in cancer. By reprogramming proteostasis to ensure efficient protein folding, it drives progression through a dual mechanism: enhancing cancer cell motility and invasiveness while concurrently activating pro‐growth and survival pathways.
Dongping Wei, Jiayan Chen, Yaping Xu
wiley   +1 more source

Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis

Advanced Science, EarlyView.
Non‐covalent interactions (NCIs) drive the formation of organic cocrystals with diverse structures and tunable optoelectronic properties. This review explores the essential factors governing these properties, highlighting how the sequential nucleation of cocrystals leads to the self‐assembly of organic hierarchical structures (OHSs).
Ya‐Nan Zhu, Jin Feng, Ying‐Xin Ma, Hong‐Tao Lin, Li‐Wei Xie, Qi‐Liang Peng, Xue‐Dong Wang   +6 more
wiley   +1 more source