Results 61 to 70 of about 1,757,856 (287)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Fixed Point Theory in Metric Type Spaces
, 2016 Written by a team of leading experts in the field, this volume presents a self-contained account of the theory, techniques and results in metric type spaces (in particular in G-metric spaces); that is, the text approaches this important area of fixed ...
Agarwal,R.P. +4 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
, 2022 This work introduces the concepts of rectangular Menger probabilistic metric (RMPM) space and rectangular Menger probabilistic b-metric (RMPbM) space as generalizations of the Menger probabilistic metric space and the Menger probabilistic b-metric space,
Reza Chaharpashlou +2 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Common fixed point theorems and applications
International Journal of Mathematics and Mathematical Sciences, 1997 The purpose of this paper is to discuss the existence of common fixed points for mappings in general quasi-metric spaces. As applications, some common fixed point theorems for mappings in probabilistic quasi-metric spaces are given. The results presented
Hemant Kumar Pathak +3 more
doaj +1 more source
A metric approach to limit operators
, 2017 We extend the limit operator machinery of Rabinovich, Roch, and Silbermann from Z^N to (bounded geometry, strongly) discrete metric spaces. We do not assume the presence of any group structure or action on our metric spaces.
Spakula, Jan, Willett, Rufus
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Completeness in Probabilistic Metric Spaces
, 2018 In this paper, we present the Cantor Intersection Theorem and a formulation of Baire Theorem in complete PM spaces. In addition, the Heine-Borel property for PM spaces is considered in detail.
Tafti, Delavar Varasteh, Azhini, Mahdi
openaire +2 more sources