Results 51 to 60 of about 134,154 (295)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Generation investment and risks modeling in a deregulated electricity market [PDF]

open access: yes, 2010
A new probabilistic model to simulate generation investment and risks applicable in a deregulated market is proposed. In this process, probabilistic production cost simulation is applied to simulate energy dispatches.
Limbu, Tika Ram   +2 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Approach For Autonomous Control Of Intralogistics Considering Deterministic And Probabilistic Material Demand Information In Flexible Production Systems

open access: yesProceedings of the Conference on Production Systems and Logistics
In today's dynamic production landscape, flexible and resilient production systems are essential to meet the constant changes in internal product and production requirements as well as external market and customer demands.
Schuhmacher, Jan   +3 more
doaj   +1 more source

A Simulation-based Search Technique for Determination of Process Parameters with Stochastic Tool Lives

open access: yesJournal of King Saud University: Engineering Sciences, 2004
This paper presents a simulation-based search approach for the machining economics problem with stochastically distributed tool lives. It is evident that the life of cutting tools used in machining centers is modeled using proper probabilistic methods ...
Abdulrahman M.A. Al-Ahmari
doaj   +1 more source

A New Strategy to Improve the Performance of PDP-Systems Simulators [PDF]

open access: yes, 2015
One of the major challenges that current P systems simulators have to deal with is to be as efficient as possible. A P system is syntactically described as a membrane structure delimiting regions where multisets of objects evolve by means of evolution
Graciani Díaz, Carmen   +2 more
core   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

What Do Large Language Models Know About Materials?

open access: yesAdvanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer   +2 more
wiley   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

open access: yesAdvanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice   +2 more
wiley   +1 more source

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