Results 71 to 80 of about 272,931 (273)
Unsupervised empirical Bayesian multiple testing with external covariates
, 2008 In an empirical Bayesian setting, we provide a new multiple testing method, useful when an additional covariate is available, that influences the probability of each null hypothesis being true.
Ferkingstad, Egil +4 more
core +2 more sources
Adjusted empirical likelihood with high-order precision [PDF]
, 2010 Empirical likelihood is a popular nonparametric or semi-parametric statistical method with many nice statistical properties. Yet when the sample size is small, or the dimension of the accompanying estimating function is high, the application of the ...
Chen, Jiahua, Liu, Yukun
core +2 more sources
Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition
Advanced Science, EarlyView.Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han +9 more
wiley +1 more source
Some Properties of a Recently Introduced Approach to Ordinal Regression
Austrian Journal of Statistics, 2016 The statistical properties of a novel approach to ordinal regression which was only recently introduced in the literature are discussed. It is shown that for ordinal explanatory variables the approach is equivalent to isotonic regression, with some ...
Florian Frommlet
doaj +1 more source
Confidence bands in nonparametric time series regression
, 2008 We consider nonparametric estimation of mean regression and conditional variance (or volatility) functions in nonlinear stochastic regression models.
Wu, Wei Biao, Zhao, Zhibiao
core +2 more sources
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
Advanced Science, EarlyView.OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
A Corrected Criterion for Selecting the Optimum Number of Principal Components
Austrian Journal of Statistics, 2016 Determining the optimum number of components to be retained is a key problem in principal component analysis (PCA). Besides the rule of thumb estimates there exist several sophisticated methods for automatically selecting the dimensionality of the data ...
Hannes Kazianka, Jürgen Pilz
doaj +1 more source
Efficient Monte Carlo for high excursions of Gaussian random fields
, 2012 Our focus is on the design and analysis of efficient Monte Carlo methods for computing tail probabilities for the suprema of Gaussian random fields, along with conditional expectations of functionals of the fields given the existence of excursions above ...
Adler, Robert J. +2 more
core +1 more source
The quenched invariance principle for random walks in random environments admitting a bounded cycle representation [PDF]
, 2008 We derive a quenched invariance principle for random walks in random environments whose transition probabilities are defined in terms of weighted cycles of bounded length.
Deuschel, Jean-Dominique +1 more
core +2 more sources
Intelligent Stain‐Free Histology on Structural Colorimetric Nanocavities
Advanced Science, EarlyView.Chen and Gan et al. introduce a label‐free imaging platform using inexpensive Nanocavity‐on‐Silicon (NOS) slides. These slides transform subtle tissue variations into vivid structural colors, enabling high‐contrast histological imaging under a regular optical microscope. This stain‐free approach reveals morphological details comparable to traditional H&
Qizhe Chen +18 more
wiley +1 more source