Results 131 to 140 of about 3,100,090 (389)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Estimating subjective probabilities

open access: yesJournal of Risk and Uncertainty, 2014
Subjective probabilities play a central role in many economic decisions and act as an immediate confound of inferences about behavior, unless controlled for.
Steffen Andersen   +8 more
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Applications of Decisions under Uncertainty in the Case of Omniasig-Life Insurance S.A. [PDF]

open access: yesInformatică economică, 2006
Uncertainty is given because we don’t know the nature state event. The company can only estimate the demand of policies in order to estimate the received premiums.
Stelian STANCU
doaj  

Extended Probabilities: Mathematical Foundations [PDF]

open access: yesarXiv, 2009
There are important problems in physics related to the concept of probability. One of these problems is related to negative probabilities used in physics from 1930s. In spite of many demonstrations of usefulness of negative probabilities, physicists looked at them with suspicion trying to avoid this new concept in their theories. The main question that
arxiv  

Possibilities for Probabilities

open access: yes, 2017
In ordinary situations involving a small part of the universe, Born's rule seems to work well for calculating probabilities of observations in quantum theory.
Page, Don N.
core  

Probabilities of counterfactuals and counterfactual probabilities

open access: yesJournal of Applied Logic, 2014
Probabilities figure centrally in much of the literature on the semantics of conditionals. I find this surprising: it accords a special status to conditionals that other parts of language apparently do not share. I critically discuss two notable 'probabilities first' accounts of counterfactuals, due to Edgington and Leitgeb.
openaire   +3 more sources

Updating Probabilities

open access: yesJournal of Artificial Intelligence Research, 2003
As examples such as the Monty Hall puzzle show, applying conditioning to update a probability distribution on a ``naive space'', which does not take into account the protocol used, can often lead to counterintuitive results. Here we examine why. A criterion known as CAR (``coarsening at random'') in the statistical literature characterizes when ...
Grunwald, Peter D., Halpern, Joseph Y.
openaire   +4 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Editorial: From Tsunami Science to Hazard and Risk Assessment: Methods and Models

open access: yesFrontiers in Earth Science, 2021
Stefano Lorito   +4 more
doaj   +1 more source

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