Results 101 to 110 of about 2,561,356 (330)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

On joint Weibull probability density functions

Applied Mathematics Letters, 2005
AbstractTwo important results for the joint probability density function of the Weibull distribution are derived.
openaire   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

A note about the deterministic property of characteristic functions

Nonlinear Analysis, 2018
We study an extension property for characteristic functions f : Rn → C of probability measures. More precisely, let f be the characteristic function of a probability density φ on Rn, and let Uσ = {x ∈ Rn: mink|xk| > σ}, σ > 0, be a neighborhood of ...
Saulius Norvidas
doaj   +1 more source

Characterization and Assessment of Projection Probability Density Function and Enhanced Sampling in Self-Collimation SPECT. [PDF]

IEEE Trans Med Imaging, 2023
Zhang D, Lyu Z, Liu Y, He ZX, Yao R, Ma T.   +5 more
europepmc   +1 more source

Not All Probability Density Functions Are Tomograms

Entropy
This paper delves into the significance of the tomographic probability density function (pdf) representation of quantum states, shedding light on the special classes of pdfs that can be tomograms. Instead of using wave functions or density operators on Hilbert spaces, tomograms, which are the true pdfs, are used to completely describe the states of ...
Liubov A. Markovich, Justus Urbanetz, Vladimir I. Man’ko   +2 more
openaire   +5 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Applying the Moment Generating Functions to the Study of Probability Distributions [PDF]

Informatică economică, 2007
In this paper, we describe a tool to aid in proving theorems about random variables, called the moment generating function, which converts problems about probabilities and expectations into problems from calculus about function values and derivates.
doaj  

Newdistns: An R Package for New Families of Distributions

Journal of Statistical Software, 2016
The contributed R package Newdistns written by the authors is introduced. This package computes the probability density function, cumulative distribution function, quantile function, random numbers and some measures of inference for nineteen families of ...
Saralees Nadarajah, Ricardo Rocha
doaj   +1 more source