Results 111 to 120 of about 225,906 (328)
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu +18 more
wiley +1 more source
Calculating effective gun policies
Following recent shootings in the USA, a debate has erupted, one side favoring stricter gun control, the other promoting protection through more weapons.
Komarova, Natalia L., Wodarz, Dominik
core
Calculation model of killing probability of explosion shock wave based on ovepressure and impulse
Based on the characteristics of the explosion injuries on the human body, a calculation model for evaluating the casualty probability of people in the explosion power field is established, which is directed against the damage caused by the changes of overpressure and impulse during explosion. By combining with the characteristics of explosion injuries,
openaire +1 more source
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang +17 more
wiley +1 more source
Estimated number of birds killed by domestic cats in Colombia
Wildlife mortality caused by domestic cats is evident where free-roaming house cats are present in the tropical Andes region, a phenomenon for which there is a lack of scientific reports.
Raul E. Sedano-Cruz
doaj
On the survival probability of a random walk in random environment with killing
We consider one dimensional random walks in random environment where every time the process stays at a location, it dies with a fixed probability. Under some mild assumptions it is easy to show that the survival probability goes to zero as time tends to infinity. In this paper we derive formulas for the rate with which this probability decays. It turns
openaire +2 more sources
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong +13 more
wiley +1 more source
The many dimensions of combination therapy: How to combine antibiotics to limit resistance evolution
In combination therapy, bacteria are challenged with two or more antibiotics simultaneously. Ideally, separate mutations are required to adapt to each of them, which is a priori expected to hinder the evolution of full resistance.
Christin Nyhoegen +2 more
doaj +1 more source
The construction sector is predominantly characterized by outdoor work, where workers are continuously exposed to environmental factors such as air pollution.
Minsu Lee, Jaewook Jeong, Louis Kumi
doaj +1 more source
Effects of Information about Invasive Species on Risk Perception and Seafood Demand by Gender and Race [PDF]
In this paper we consider the effects of negative and positive risk information on perceived seafood risks and seafood consumption by gender and race. The data is from a Mid-Atlantic survey of coastal seafood consumers.
George R. Parsons +3 more
core

