Results 51 to 60 of about 225,906 (328)

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

Chemotherapy-induced release of circulating-tumor cells into the bloodstream in collective migration units with cancer-associated fibroblasts in metastatic cancer patients

open access: yesBMC Cancer, 2020
Background Recent studies have shown that chemotherapy destabilizes the blood vasculature and increases circulating tumor cell (CTC) influx into the circulation of metastatic cancer patients (Met-pa).
Nerymar Ortiz-Otero   +3 more
doaj   +1 more source

Marked Long‐term Improvement in Lung Function in Melanoma Differentiation‐associated Protein 5 (MDA5) Antibody Positive Dermatomyositis Patients: Experience of a Single Center Longitudinal Cohort in North America

open access: yesArthritis Care &Research, Accepted Article.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah   +8 more
wiley   +1 more source

Antibiotic-induced population fluctuations and stochastic clearance of bacteria

open access: yeseLife, 2018
Effective antibiotic use that minimizes treatment failures remains a challenge. A better understanding of how bacterial populations respond to antibiotics is necessary.
Jessica Coates   +5 more
doaj   +1 more source

Increasing paths on N-ary trees [PDF]

open access: yes, 2014
Consider a rooted $N$-ary tree. To every vertex of this tree, we attach an i.i.d. continuous random variable. A vertex is called accessible if along its ancestral line, the attached random variables are increasing.
Chen, Xinxin
core   +2 more sources

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

open access: yesArthritis Care &Research, Accepted Article.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high magnitude stress.
Jay B. Higgs   +15 more
wiley   +1 more source

Pharmacokinetics and Pharmacodynamics of Colistin Methanesulfonate in Healthy Chinese Subjects after Multi-Dose Regimen

open access: yesAntibiotics, 2022
Colistin methanesulfonate (CMS) is an important treatment option for infections caused by carbapenem-resistant Gram-negative organisms (CROs). This study evaluated the pharmacokinetic/pharmacodynamic (PK/PD) profiles and safety of CMS in Chinese subjects
Yaxin Fan   +19 more
doaj   +1 more source

Discovering Job Preemptions in the Open Science Grid

open access: yes, 2018
The Open Science Grid(OSG) is a world-wide computing system which facilitates distributed computing for scientific research. It can distribute a computationally intensive job to geo-distributed clusters and process job's tasks in parallel.
Bockelman, Brian   +3 more
core   +1 more source

Who Should Bear the Risk When Self-Driving Vehicles Crash? [PDF]

open access: yes, 2021
The moral importance of liability to harm has so far been ignored in the lively debate about what self-driving vehicles should be programmed to do when an accident is inevitable.
Kauppinen, Antti
core  

Interactions between Molten High‐Silicon Electrical Steels and Carbon‐Bonded MgO Refractories Based on Recyclates

open access: yesAdvanced Engineering Materials, EarlyView.
This study examines how several molten high‐silicon electrical steels interact with both conventional and recycled MgO–C refractories. For this, various immersion experiments are conducted. In addition to infiltration, a number of mechanisms are identified and explained that control the corrosion of the refractory material.
Lukas Neubert   +7 more
wiley   +1 more source

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