Results 131 to 140 of about 6,227,183 (247)

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Which Optimal Design For LLDAs? [PDF]

Lottery-linked deposit accounts are financial assets that provide an interest rate determined by a lottery. The aim of this study is to determine the optimal design of these financial assets (under cumulative prospect theory (CPT) framework).
Marie Pfiffelmann
core  

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

EMPLOYEE STOCK OPTIONS INCENTIVE EFFECTS: A CPT-BASED MODEL [PDF]

This paper examines the incentives from stock options for loss-averse employees subject to probability weighting. Employing the certainty equivalence principle, I built on insights from Cumulative Prospect Theory (CPT) to derive a continuous time model ...
Hamza Bahaji
core  

Accounting for Withdrawal of Life-Sustaining Treatment in the Analysis of Traumatic Brain Injury Studies

Neurotrauma Reports
Studies that aim to evaluate outcomes after severe traumatic brain injury (TBI) must account for patients who die after withdrawal of life-sustaining treatment (WLST). If we are willing to assume that some of the patients who die of WLST might have had a
Brian C. Healy, Brian L. Edlow, Yelena G. Bodien   +2 more
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

“Technical” method for estimating the probability of sovereign defaults

Мир новой экономики, 2018
The article discusses a simple method for estimating the probability of sovereign default function based on the determination of the key factors for the assessment of default and their weighting factors according to the statistics for the group of ...
E. V. Balatsky
doaj  

Dynamic patterns of anemia and cognitive function: a longitudinal cohort study based on the China Health and Retirement Longitudinal Study

BMC Public Health
Background Anemia is associated with cognitive decline, but the influence of its temporal patterns on cognitive trajectories remains unknown. This study investigated the longitudinal association between dynamic anemia patterns (persistent, intermittent ...
Junjie Cui, Qiucheng Zhang, Xianjun Lv, Liubing Zhao, Wei Xu, Liang Wang, Shuai Pei, Wei Zhang, Mengting Zhuang   +8 more
doaj   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Moderate or severe aortic valve disease in patients with successful rheumatic mitral and tricuspid valve repair: Efforts to repair valveCentral MessagePerspective

JTCVS Open
Objective: The management of aortic valve (AV) disease in patients with rheumatic heart disease (RHD) undergoing multivalve surgery remains uncertain. This study aimed to compare the long-term outcomes of AV repair versus AV replacement in patients with ...
Zhou Liu, MD, Chuang Liu, MD, Ruifei Liu, MM, Yazhe Zhang, MM, Jiajun Liang, MM, Jie Han, MD, Xu Meng, MD, Meili Wang, PhD, Hongjia Zhang, MD, Wenjian Jiang, MD   +9 more
doaj   +1 more source