Results 151 to 160 of about 1,851,676 (299)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A sequentially activated afterglow probe for AND-gated imaging of alpha-fetoprotein in hepatocellular carcinoma. [PDF]

Bioact Mater
Du H, Li Y, Zheng X, Peng C, Liu Q, Tong W, Zhou Q, Liu Z, Peng Y.   +8 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Improved specificity of a probe-based real-time PCR for the detection of Dirofilaria immitis in canine blood. [PDF]

Parasit Vectors
Kelly MA, Sanders TL, Starnes A, Orr E, Luksovsky JL, Sobotyk C, Hakimi H, Weerarathne P, Budke CM, Verocai GG.   +9 more
europepmc   +1 more source

Wilkinson Microwave Anisotropy Probe (WMAP)

The Wilkinson Microwave Anisotropy Probe (MAP) mission reveals the conditions of the early universe by measuring the comic microwave background radiation in the sky.

core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

A Quinoline-Benzimidazole Probe for Efficient Detection of Imidacloprid: Mechanisms and Applications. [PDF]

Molecules
Wang HF, Zhu J, He YW, Wang M, Zhang JX, Zhuang YW, Suo ZG, Zhou SQ, Zhang YC, Xie HJ.   +9 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Bioorthogonal dual-channel imaging of NO and H₂S reveals redox imbalance in atherosclerotic plaques. [PDF]

Chem Sci
Xu J, Xia X, Li P, Tang Y, Zhang W, Wang H, Zhang W, Tang B.   +7 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source