Results 31 to 40 of about 338,189 (265)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
AgronomyRecent studies have focused on using big-data-based machine learning to address the effects of climate change scenarios on the production and quality of medicinal plants.
Hyunjo Lee +5 more
doaj +1 more source
Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram, 2017 This research with the aim to know the influence of the use of Creative Problem solving learning model on problem solving skills and cognitive learning outcomes of grade X SMA Islam Al-Ma'arif Pandan Indah Lesson 2016/2017. Population in this research is
Rosmianti Lestari Mbembok +2 more
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Efektivitas E-Modul Sistem Pencernaan Berbasis Problem Solving Terhadap Kemampuan Pemecahan Masalah
JIPI (Jurnal IPA dan Pembelajaran IPA), 2021 Learning during the Covid-19 pandemic has largely shifted to online learning. In response to this, it is necessary to prepare teaching materials that support online learning, one of which is the use of electronic models or e-modules.
Irvan Permana* +2 more
doaj +1 more source
CoRR, 2016 13 Pages, 8 Tables, 2 Figures. Proc. 16th EuSpRIG Conf.
Mária Csernoch, Piroska Biró
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Al-Jabar, 2015 Lack of mathematical problem solving ability of students in Bandar Lampung MAN 2 due learners trouble completing math problems and students rarely ask questions or express ideas workmanship. This study aims to determine the effect of mathematical problem
Muhamad Syazali
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Description and impact of a distance mathematics course for Grade 10 to 12 teachers
Pythagoras, 2007 This paper explores the impact of a one-year in-service distance education mathematics course that follows a problem-solving approach. The course aims to develop teachers’ mathematical thinking skills.
Gerrit Stols +2 more
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ASSESSING STUDENTS’ MATHEMATICAL PROBLEM-SOLVING ABILITY
Aksioma: Jurnal Program Studi Pendidikan Matematika, 2023 Students' ability to solve mathematical problems is the most important part of learning mathematics. Therefore, assessing students' ability to solve mathematical problems is one of the tasks of mathematics teachers that must be done.
Sufyani Prabawanto +2 more
doaj +1 more source