We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Improving Mathematical Problem-solving Ability and Self-confidence of High School Students Through Contextual Learning Model [PDF]
The purposes of this study are: (1) to know if students' mathematical problem-solving ability taught by contextual learning model is higher than students taught by expository learning, (2) to know if students' self-confidence taught by contextual ...
Mukhtar, M. (Mukhtar) +2 more
core
ABSTRACT This article explores how artificial intelligence (AI) can support online adult learning by aligning with Knowles’ four principles of andragogy: involvement, experience, problem‐centeredness, and relevance. Three activities were analyzed using a comparative case study (CCS) method.
Xi Lin, Steve W. Schmidt
wiley +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu +16 more
wiley +1 more source
Pengaruh Metode Problem Solving Secara Algoritmik Dan Heuristik Terhadap Prestasi Belajar Ditinjau Dari Kemampuan Metakognisi Siswa Pada Materi Kelarutan Dan Hasil Kali Kelarutan Kelas XI Mia Di SMA N 5 Surakarta [PDF]
Penelitian ini bertujuan untuk mengetahui: (1) pengaruh metode problem solving secara algoritmik dan heuristik terhadap prestasi belajar siswa materi kelarutan dan hasil kelarutan; (2) pengaruh kemampuan metakognisi terhadap prestasi belajar siswa materi
Eko Setyowati, Widiastuti Agustina +2 more
core
Using chess as a tool for promoting 5th grade students’ mathematics problem solving abilities [PDF]
The purpose of this study was to investigate the effect of chess training on 5thgrade students’ problem solving abilities. The review of literature started with the research on novice and expert problem solvers.
Mohammad Ali Rezvāni +2 more
doaj
This study aimed to describe the students’ critical thinking processes in solving plane geometry problems based on cognitive styles and gender styles. This research used the descriptive qualitative method. The subjects of this study were four junior high
Fulgensius Efrem Men +3 more
doaj +1 more source
Application of Binary Slime Mould Algorithm for Solving Unit Commitment Problem [PDF]
Md. Sayed Hasan Rifat +6 more
openalex +1 more source
Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker +9 more
wiley +1 more source

