Results 51 to 60 of about 1,322,598 (284)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Problem-solving strategies in psychiatry: differences between experts and novices in diagnostic accuracy and reasoning

Advances in Medical Education and Practice, 2013
Adel Gabriel,1,2 Claudio Violato21Departments of Psychiatry, University of Calgary, Calgary; 2Medical Education, Community Health Sciences, University of Calgary Calgary, CanadaBackground: The purpose of this study was to examine and compare diagnostic ...
Gabriel A, Violato C
doaj  

Assessing physics students’ problem-solving skills: a baseline investigation

Discover Education
Physics problem-solving ability is among the crucial skills physics students require as it enhances their conceptual understanding and develops their abilities for real-world problem-solving.
Theophile Musengimana, Lakhan Lal Yadav, Jean Uwamahoro, Gabriel Nizeyimana   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The challenge of complexity for cognitive systems [PDF]

, 2011
Complex cognition addresses research on (a) high-level cognitive processes – mainly problem solving, reasoning, and decision making – and their interaction with more basic processes such as perception, learning, motivation and emotion and (b) cognitive ...
Funke, Joachim, Gonzalez, Cleotilde, Ragni, Marco, Schmid, Ute   +3 more
core   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

The Relationship between Learning Styles and ProblemSolving Strategies in Undergraduate Nursing Students of Isfahan University of Medical Sciences Iran [PDF]

Strides in Development of Medical Education, 2017
Background & Objective: Individuals based on their learning styles have different interpretation of the environment and issues and choose different problemsolving strategies The objective of the present research was identifying the relationship between ...
Reyhaneh Taheri, Fariba Karimi
doaj  

Knowledge revision in systems based on an informed tree search strategy : application to cartographic generalisation

, 2008
Many real world problems can be expressed as optimisation problems. Solving this kind of problems means to find, among all possible solutions, the one that maximises an evaluation function. One approach to solve this kind of problem is to use an informed
Drogoul, Alexis, Duchêne, Cécile, Taillandier, Patrick   +2 more
core   +3 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Problem Solving: Economic Learning Strategies

IJOLEH : International Journal of Education and Humanities, 2023
The ability to control learning is one that teachers must possess. One of the techniques a teacher should use in the educational process is problem solving. With the use of creative and innovative learning strategies, this article intends to help teachers, in particular, comprehend how to build information in a methodical manner.
null Wahyu Muh. Syata, null Abdullah Igo B.D, null Bellona Mardhatillah Sabillah   +2 more
openaire   +1 more source