Results 91 to 100 of about 16,498,200 (273)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Computer support of group decision making [PDF]

open access: yesComputer Science Journal of Moldova, 2001
In this paper we consider techniques of computer group decision making support. The interrelation of support methods, negotiation process type, and character of problems to be managed is shown.
E.A. Trachtenherz
doaj  

The J-Box Problem [PDF]

open access: yes, 2000
The study group was presented with the problem of determining the behaviour of a web of wet cellulose fibres - called a tow - as it passes through part of the manufacturing process.
Allwright, D.J., Jones, M., Please, C.P.
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

THEORETICAL AND IDEOLOGICAL SOURCES OF IBN SINA PHILOSOPHY ON THE ISSUE OF REASON AND FAITH

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
The article examines the theoretical and ideological sources of Ibn Sina philosophy on the issue of human. The author emphasizes that the studies of Ibn Sina were based on the philosophical tradition of antiquity, on their doctrine of man as a rational ...
Saida Zakhro Takikhoni
doaj   +1 more source

The Metric Nearness Problem [PDF]

open access: yes, 2008
Metric nearness refers to the problem of optimally restoring metric properties to distance measurements that happen to be nonmetric due to measurement errors or otherwise.
Brickell, Justin   +3 more
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Pauli problem in thermodynamics [PDF]

open access: yes, 2013
A thermodynamic analogue of the Pauli problem (reconstruction of a wavefunction from the position and momentum distributions) is formulated. The coordinates of a quantum system are replaced by the inverse absolute temperature and other intensive ...
Ruuge, Artur E.
core  

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

open access: yesAging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy