Results 61 to 70 of about 16,543,141 (273)
Solved! Making the case for collaborative problem-solving [PDF]
, 2017 This report argues that the ability to solve problems with others is a crucial skill for our young people in the workplace of the future but the current education system does little to support it.
Baines, Ed +4 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The interdisciplinary problem: an analysis
Analiza i Egzystencja, 2022 The purpose of this paper is to analyze the concept of the interdisciplinary problem using the categories of the logic of questions. The problem is seen in a logical and epistemic sense: the problem is a meaning of the question, and the question is a ...
Monika Walczak
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
A Relationship Between Problem Solving Ability and Students' Mathematical Thinking [PDF]
, 2017 This research have a purpose to know is there an influence of problem solving abilty to students mathematical thinking, and to know how strong problem solving ability affect students mathematical thinking.
Delima, N. (Nita)
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
When is a problem a research problem? [PDF]
, 1992 Various definitions of and approaches to research and research problems are explored with numerous examples given. Guiding criteria for applied research are also discussed, along with potential pitfalls, the role of intuition in the process, and the ...
Cronin, Blaise
core
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Formation features of vocabulary units with a color designation component in the Yukagir language
Развитие образования, 2018 The article reveals the formation features of vocabulary units with a color designation component in the Yukagir language. The result of the study is the conclusion that the word formation of color terms in the dialects of the Yukagir language is ...
Margarita P. Lukina
doaj +1 more source
Education Sciences, 2019 Problem-oriented pedagogies have emerged as strategic way for universities to respond to an international higher education agenda that increasingly prioritises innovative, student-centred learning, and the cultivation of both civic and employability ...
Renae Acton
doaj +1 more source