Results 111 to 120 of about 1,064,620 (357)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Frontiers in Psychology, 2020 Social media plays a significant role in modern life, but excessive use of it during the COVID-19 pandemic has become a source of concern. Supported by the conservation of resources theory, the current study extends the literature on problematic social ...
Mehwish Majeed +4 more
doaj +1 more source
Cognitive deficits in problematic internet use : meta-analysis of 40 studies [PDF]
, 2019 © The Royal College of Psychiatrists 2019. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and ...
Chamberlain, Samuel R +6 more
core +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Frontiers in PsychiatryIntroductionSocial media is integral to adolescents’ lives, with the separation between adolescents’ online and offline worlds harder to distinguish. Adolescent development occurs online via the opportunity to connect with others and explore themselves ...
Sarah E. Domoff +8 more
doaj +1 more source
Effects of Celiac Disease on Religion and Language [PDF]
, 2016 Celiac disease is an autoimmune disease that prevents people from digesting gluten. The diagnosis of Celiac impacts more than physical health, it irrevocably alters a person’s conception of self. Ordinary activities like airport travel, staying in hotels,
Gustafson, Solveig L. +1 more
core +1 more source
God and the Machine: A Correlational Study on Mobile Phone Dependence, Religious Coping, and Mental Health [PDF]
, 2020 Research on the various effects of mobile phones did not begin to be published until after they had already been integrated into society. To date, the results of various studies looking into the relationship between mobile phone use and mental health ...
Bolme, Rachel
core +1 more source
Media use during adolescence: the recommendations of the Italian Pediatric Society. [PDF]
, 2019 BACKGROUND: The use of media device, such as smartphone and tablet, is currently increasing, especially among the youngest. Adolescents spend more and more time with their smartphones consulting social media, mainly Facebook, Instagram and Twitter ...
Agostiniani R +15 more
core +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source