Results 121 to 130 of about 2,052,150 (308)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Soil reinforcement with synthetic and natural fibres: a review [PDF]

open access: yes, 2020
Problematic soil is a common issue in construction activities, particularly when dealing with peat and clay soils of poor geotechnical properties. Such soils are non-homogeneous, and their properties vary greatly from place to place or, in some cases ...
Abdul Rahman, Mohd Fahrni   +6 more
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Validation of the Persian Version of the Problematic Internet Use Questionnaire (PIUQ).

open access: yesIranian Journal of Psychiatry, 2014
Objective: The most commonly used instrument for the research and treatment of excessive internet use is Young’s Internet Addiction Test (IAT). While the IAT has been translated to several languages (including Persian) and has demonstrated good ...
Hadi Ranjbar   +4 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Problematic TikTok Use and Its Association with Poor Sleep: A Cross-Sectional Study Among Greek Young Adults

open access: yesPsychiatry International
Background: TikTok use is constantly increasing, especially among young adults. Although there is a negative association between problematic TikTok use and users’ health, no study until recently has investigated the association between TikTok use and ...
Aglaia Katsiroumpa   +6 more
doaj   +1 more source

Drugs research: an overview of evidence and questions for policy [PDF]

open access: yes, 2010
In 2001 the Joseph Rowntree Foundation embarked upon a programme of research that explored the problem of illicit drugs in the UK. The research addressed many questions that were often too sensitive for the government to tackle.
Lloyd, C., McKeganey, N.
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Association Between TikTok Use and Anxiety, Depression, and Sleepiness Among Adolescents: A Cross-Sectional Study in Greece

open access: yesPediatric Reports
Introduction: TikTok use is increasing, especially among children and adolescents. However, the negative effects of TikTok use have not been sufficiently investigated.
Angeliki Bilali   +6 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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