Results 111 to 120 of about 2,396,506 (265)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Prochloraz (proc) Average Cumulative Fecundity.

open access: yes, 2016
(A) control (0 μg proc•L-1); (B) 30 μg proc•L-1; (C) 100 μg proc•L-1; (D) μg proc•L-1. Filled markers represent experimental data (cumulative fecundity divided by the number of females in a treatment group) [6]; dashed lines represent the mean of 50 ...
Daniel L. Villeneuve (299677)   +5 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

PROTEIN FRACTIONS AND IN VITRO FERMENTATION OF PROTEIN FEEDS FOR RUMINANTS

open access: yesTropical and Subtropical Agroecosystems, 2011
The objective of this study was to evaluate 20 protein feeds grouped in forages, vegetal by- products and animal by-products used for ruminant diets. Protein fractions (PF): A, non-protein nitrogen (NPN); B1, buffer-soluble protein; B2, buffer-insoluble,
Angel L. Guevara-Mesa   +6 more
doaj  

Using linear mixed model to analyze the longitudinal data [PDF]

open access: yes, 2007
The purpose of this research is to analyze longitudinal data using linear mixed model with application to voltage-dependent motility and/ or stiffness changes of the hair bundle of outer hair cells (OHCs).
Wang, Jing
core  

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Comparación de los procedimientos GLM y MIXED del SAS® para analizar diseños de parcelas divididas con bloques al azar (COMPARING THE SAS GLM AND MIXED PROCEDURES FOR SPLIT-PLOT DESIGNS IN RANDOMIZED COMPLETE BLOCKS) [PDF]

open access: yes, 2001
PROC GLM of SAS has been the most common routine to analyze data coming from split-plot designs. However, this procedure was developed to evaluate fixed models and it does not consider this type of design that relates more to a mixed model with fixed and
José L. Gil
core  

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

open access: yesFEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

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